A nurse is preparing to administer Lactated Ringer's 1000 mL IV to infuse over 6 hours. The drop factor of the manual IV tubing is 10 gtt/mL. What is the flow rate in gtt/min? (Round to the nearest whole number & fill in the blank with the numerical value only)

A. Triptans should be administered only after other pain medications have been tried: Triptans are first-line agents for moderate to severe migraines and do not require prior use of other analgesics. Delaying their use can reduce effectiveness and prolong the migraine episode.
B. Triptans should be administered at the onset of aura symptoms: Triptans are not recommended during the aura phase, especially for patients with migraines that involve motor or sensory auras, due to concerns about vasoconstrictive effects before pain begins. They are intended for use when headache pain starts.
C. Triptans are most effective when taken early in the migraine attack, at the onset of pain: Triptans work by stimulating serotonin receptors, causing cranial vasoconstriction and reducing neurogenic inflammation. They are most effective when taken as soon as the headache phase begins, not during aura or late in the attack.
D. Triptans can be safely administered every hour until pain relief is achieved: Triptans have strict dosing intervals due to their vasoconstrictive properties, and exceeding recommended doses can lead to cardiovascular complications. They should not be taken more frequently than prescribed.

A. "If my pain persists, I can safely increase the dose to 1500 mg every 4–6 hours.": This dose exceeds the maximum safe limit for acetaminophen. The recommended adult dose is no more than 1000 mg per dose and 4000 mg per day. Exceeding this can lead to serious hepatotoxicity, especially with prolonged use or preexisting liver conditions.
B. "I should use caution when taking acetaminophen with warfarin as it may affect my INR levels.": Acetaminophen can increase the anticoagulant effect of warfarin, possibly elevating INR and increasing the risk of bleeding. Regular monitoring is recommended when both drugs are used concurrently.
C. "I need to be cautious when taking other medications that may contain acetaminophen.": Many over-the-counter medications, such as cold and flu remedies, also contain acetaminophen. Accidental overdose can occur if this is not considered when calculating total daily intake.
D. "I should contact my healthcare provider if I experience yellowing of the skin or eyes.": Jaundice may be a sign of liver damage or failure due to acetaminophen toxicity. Early recognition of this symptom is critical for preventing serious complications.