A nurse is preparing to administer the initial dose of penicillin G IM to a client. The nurse should monitor for which of the following as an indication of an allergic reaction following the injection?

This is the priority for the nurse to report to the provider because cefuroxime is a cephalosporin antibiotic that can cause serious or life-threatening allergic reactions in people who are allergic to penicillin. The nurse should not administer cefuroxime to this client until the provider is notified and an alternative antibiotic is prescribed.

Choice A is wrong because the client has a BUN level of 18 mg/dL, which is within the normal range of 7 to 20 mg/dL.

This does not indicate any renal impairment or adverse reaction to cefuroxime.

Choice B is wrong because the client reports a history of nausea with cefuroxime, which is a common side effect of this drug.

The nurse should instruct the client to take cefuroxime with food to reduce nausea, but this is not a priority to report to the provider.

Choice D is wrong because the client takes aspirin daily, which does not interact with cefuroxime.

The nurse should monitor the client for any signs of bleeding or bruising while taking aspirin, but this is not a priority to report to the provider.

Raloxifene is a medication used to prevent and treat osteoporosis in postmenopausal women.

Osteoporosis is a condition that causes bones to become thin and weak, increasing the risk of fractures.

Raloxifene belongs to a class of drugs called selective estrogen receptor modulators (SERMs), which mimic the effects of estrogen on bone density. Choice B is wrong because raloxifene may increase the risk of deep-vein thrombosis (DVT), a type of blood clot that forms in a vein deep in the body. DVT can cause pain, swelling, and redness in the affected limb, and can lead to serious complications such as pulmonary embolism (PE), a blood clot in the lung.

Raloxifene should not be used by people who have or had DVT or PE. Choice C is wrong because raloxifene is not used to treat urinary tract infection (UTI), an infection that affects the bladder, kidneys, or ureters. UTI can cause symptoms such as burning or pain when urinating, frequent or urgent urination, blood in the urine, or fever.

UTI is usually treated with antibiotics.

Choice D is wrong because raloxifene is not used to treat hypothyroidism, a condition that occurs when the thyroid gland does not produce enough thyroid hormone.

Thyroid hormone regulates the body’s metabolism, growth, and development. Hypothyroidism can cause symptoms such as fatigue, weight gain, cold intolerance, dry skin, hair loss, or depression.

Hypothyroidism is usually treated with synthetic thyroid hormone replacement.