A nurse is preparing to administer vancomycin 250 mg PO. The amount available is vancomycin 125 mg/ capsule. How many capsules should the nurse administer to the client with each dose? (Round to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

A. Place all clients who have manifestations on contact precautions: Given the suspicion of Clostridium difficile infection due to the development of watery diarrhea in multiple clients, it is appropriate to place these clients on contact precautions until the diagnosis is confirmed or ruled out. Contact precautions help prevent the spread of the infection by requiring healthcare workers to wear gloves and gowns when entering the room.
B. Obtain stool cultures from all clients on the nursing unit: While obtaining stool cultures may be necessary to confirm the diagnosis of C. difficile infection, implementing contact precautions is more immediate and necessary to prevent transmission.
C. Request the providers to initiate antibiotic therapy for every client on the unit: Initiating antibiotic therapy for every client on the unit without confirmation of C. difficile infection is not appropriate and may contribute to antibiotic resistance.

D. Perform hand hygiene with an alcohol-based agent: Hand hygiene is essential in preventing the spread of infection, but in the case of C. difficile, handwashing with soap and water is recommended over alcohol-based hand sanitizers due to the spore-forming nature of the bacteria.

A. Antibiotic dosages below the minimum concentration are prescribed: This statement is inaccurate. MRSA infections typically require higher than normal doses of antibiotics due to their resistance. Prescribing below the minimum concentration would likely be ineffective.
B. Broad-spectrum antibiotics are used whenever possible: While broad-spectrum antibiotics may cover a wide range of bacteria, they are not always the best choice for treating MRSA.
Targeted antibiotics effective against MRSA are preferred to minimize the risk of further antibiotic resistance.
C. Antibiotics are prescribed only when a viral infection is present: MRSA is a bacterial infection, not viral. Antibiotics are indicated for bacterial infections like MRSA but not for viral infections.
D. Infections become resistant to high doses of antibiotics: This statement is accurate. MRSA is resistant to many common antibiotics, and overuse or inappropriate use of antibiotics can contribute to the development of antibiotic-resistant strains. High doses of antibiotics may not be effective against MRSA, as the bacteria have developed mechanisms to resist their action.