A nurse is reviewing a client's medical history before administering a new prescription for atropine. Which of the following client conditions is contraindicated?

A. Hydroxyzine: Hydroxyzine is an antihistamine medication commonly used to treat anxiety and allergic reactions. While it may have interactions with other medications, it is not specifically contraindicated with mirtazapine. However, caution should be exercised when combining medications with sedative effects.

B. Clozapine: Clozapine is an antipsychotic medication primarily used to treat schizophrenia in cases where other medications have not been effective. While it may have interactions with other drugs, it is not specifically contraindicated with mirtazapine. However, caution should be exercised when combining multiple psychotropic medications.

C. Linezolid: Linezolid is an antibiotic medication used to treat certain bacterial infections, including those caused by drug-resistant organisms. It is contraindicated with mirtazapine due to the risk of serotonin syndrome, a potentially life-threatening condition that can occur when serotonin levels in the brain become too high. Concurrent use of linezolid and mirtazapine can lead to serotonin syndrome due to their effects on serotonin levels.

D. Nortriptyline: Nortriptyline is a tricyclic antidepressant medication used to treat depression and various other conditions. While it may interact with other drugs, it is not specifically contraindicated with mirtazapine. However, caution should be exercised when combining multiple antidepressant medications due to the risk of serotonin syndrome.

A) Extravasation:
Extravasation of dopamine is a significant concern as it can cause tissue necrosis, but it requires immediate intervention to stop the infusion and treat the site, not an increase in the infusion rate. Increasing the rate of infusion in this case would worsen the extravasation and potential tissue damage.

B) Headache:
A headache can be a side effect of dopamine infusion, often related to vasoconstriction and hypertension. However, it is not an indicator to increase the infusion rate. Instead, the nurse might need to assess and manage the headache separately.

C) Hypotension:
Correct. Hypotension is a primary indication that the dopamine infusion rate should be increased. Dopamine is used to support blood pressure in patients with septic shock by increasing cardiac output and vasoconstriction. If the client's blood pressure remains low, it indicates that the current dose of dopamine is insufficient, and the rate should be titrated up to achieve the desired hemodynamic effect.

D) Chest pain:
Chest pain can be a serious side effect of dopamine, indicating potential myocardial ischemia due to increased cardiac workload and oxygen demand. If the client experiences chest pain, the nurse should not increase the infusion rate but should instead assess for signs of cardiac ischemia or infarction and notify the healthcare provider immediately.