A nurse is reviewing a client’s medical history before administering a new prescription for atropine. Which of the following client conditions is contraindicated?

A. “You should take this medication once each day at bedtime.” This statement is incorrect because rifampin is typically taken on an empty stomach, either 1 hour before or 2 hours after a meal, to ensure optimal absorption. Taking it at bedtime is not a standard recommendation.
B. “You can continue to wear soft contact lenses while taking this medication.” This statement is incorrect because rifampin can cause discoloration of bodily fluids, including tears, which can stain soft contact lenses. Patients are usually advised to avoid wearing soft contact lenses during treatment.
C. “This medication will not interfere with the effectiveness of oral contraceptives.” This statement is incorrect because rifampin is known to reduce the effectiveness of oral contraceptives. Patients should be advised to use an alternative or additional form of contraception while taking rifampin.
D. “Your urine will turn orange while you are taking this medication.” This statement is correct. Rifampin commonly causes a harmless discoloration of urine, sweat, saliva, and tears to an orange or reddish color. Patients should be informed about this side effect to avoid unnecessary concern.

A. “You require TPN because you have a low platelet count” is incorrect. TPN is not prescribed for low platelet counts; it is used for nutritional support.
B. “You will receive TPN through a central vein” is correct. TPN is typically administered through a central venous catheter because it is a hypertonic solution that can irritate peripheral veins.
C. “You require TPN because your glucose is too high” is incorrect. TPN is not used to manage high glucose levels; it is used for providing nutrition when oral or enteral feeding is not possible.
D. “You will receive TPN for the next 6 months” is incorrect. The duration of TPN therapy varies depending on the client’s condition and nutritional needs.