A nurse is reviewing the laboratory data of a client who is receiving filgrastim. Which of the following laboratory values should the nurse monitor to evaluate the effectiveness of the treatment?

Potassium level

BUN

INR

WBC count

Answer and Explanation

The Correct Answer is D

Filgrastim is a medication that stimulates the production of white blood cells (WBCs), particularly neutrophils, which are a type of WBC important for fighting infections. An increase in the WBC count would indicate that filgrastim is effectively stimulating the production of WBCs, which is desirable, especially in clients who are at risk of neutropenia (low WBC count) due to chemotherapy or other factors.

Monitoring potassium levels is important for clients receiving certain medications or experiencing conditions that can affect potassium balance, but it is not specifically related to filgrastim therapy.

BUN is a measure of kidney function and hydration status, but it is not typically monitored to evaluate the effectiveness of filgrastim treatment.

INR is a measure of blood clotting and is primarily monitored in clients receiving anticoagulant therapy, such as warfarin. It is not relevant to filgrastim therapy.

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Correct Answer is C

Explanation

Oxycodone is an opioid analgesic medication that acts primarily on the central nervous system (CNS) to relieve pain. One of the side effects of opioids like oxycodone is respiratory depression, where breathing becomes slow and shallow. This effect occurs because opioids suppress the activity of the respiratory centers in the brainstem, leading to decreased respiratory rate and depth.

A-oxycodone has no effect on sodium channels

B-opioids cause vasodilation of cerebral vessels but this does not directly affect respiration D-Opioids have no effect on prostaglandin synthesis

A. PT B. Total iron-binding capacity C. WBC D. PTT

Correct Answer is A

Explanation

PT measures the time it takes for blood to clot, and it is particularly relevant for clients taking warfarin because warfarin works by inhibiting the synthesis of certain clotting factors, including factors II, VII, IX, and X, which are involved in the PT pathway. Monitoring PT levels helps ensure that the client is receiving an appropriate dose of warfarin to prevent clot formation without causing excessive bleeding.
B. Total iron-binding capacity (TIBC) is a test used to assess iron levels in the blood and is unrelated to warfarin therapy.
C. WBC (White Blood Cell count) is a test used to assess the number of white blood cells in the blood and is unrelated to warfarin therapy.
D. PTT (Partial Thromboplastin Time) is a test used to evaluate the intrinsic and common pathways of the coagulation cascade. It is used in the monitoring of heparin anticoagulant therapy. It is not typically used to monitor warfarin therapy

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A nurse is reviewing the laboratory data of a client who is receiving filgrastim. Which of the following laboratory values should the nurse monitor to evaluate the effectiveness of the treatment?

Nursing Test Bank

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