A nurse is reviewing the list of current medications for a client who is to start a new prescription for carbamazepine. The nurse should identify which of the following medications interacts with carbamazepine.
Estrogen-progestin combination
Nicotine transdermal system
Diphenhydramine
Beclomethasone
The Correct Answer is A
A. Estrogen-progestin combination:
Correct Answer: This medication interacts with carbamazepine.
Explanation: Carbamazepine is known to induce certain liver enzymes, including cytochrome P450 enzymes. These enzymes play a role in the metabolism of various medications, including estrogen-containing oral contraceptives (estrogen-progestin combinations). Carbamazepine can increase the metabolism of estrogen-progestin combinations, potentially reducing their effectiveness and increasing the risk of contraceptive failure. Therefore, this interaction can lead to decreased contraceptive efficacy and the potential for unintended pregnancy.
B. Nicotine transdermal system:
Incorrect Explanation: This medication does not interact with carbamazepine.
Explanation: Nicotine replacement therapies, such as nicotine transdermal systems, are not known to have significant interactions with carbamazepine. These therapies are primarily used to aid in smoking cessation and do not share metabolic pathways with carbamazepine.
C. Diphenhydramine:
Incorrect Explanation: This medication does not interact with carbamazepine.
Explanation: Diphenhydramine is an antihistamine used for allergies and as a sleep aid. It does not have a well-established interaction with carbamazepine. However, it's important to note that carbamazepine can have central nervous system (CNS) effects, so caution should be exercised when combining it with other medications that also have CNS effects.
D. Beclomethasone:
Incorrect Explanation: This medication does not interact with carbamazepine.
Explanation: Beclomethasone is a corticosteroid used to manage inflammation associated with conditions like asthma and allergic rhinitis. It is not known to interact with carbamazepine. These two medications have different mechanisms of action and do not share significant metabolic pathways.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Instruct the client to increase his fluid intake: While adequate fluid intake is generally important for various reasons, increasing fluid intake would not alter the orange-red discoloration caused by rifampin. This side effect is due to the drug's action on body fluids, not dehydration.
B. Prepare the client for dialysis: Dialysis is not indicated for the harmless orange-red discoloration caused by rifampin. Dialysis is typically used for clients with kidney failure or significant electrolyte imbalances, and it would not address this specific side effect.
C. Document this as an expected finding.
Explanation:
Rifampin, an antibiotic commonly used in the treatment of tuberculosis (TB), can cause a harmless side effect known as "orange-red discoloration." This can affect bodily fluids such as urine, sweat, and tears. This is not a harmful effect and does not indicate a need for any specific intervention. Therefore, the nurse should document this as an expected finding due to the client's use of rifampin.
D. Check the client's liver function test results: The orange-red discoloration is not related to liver function, so checking liver function test results would not provide relevant information about this particular side effect.
Correct Answer is B
Explanation
A. Administer 2 sprays of nicotine nasal spray in each nostril with each dose: Nicotine nasal spray is administered as a single spray in each nostril with each dose.
B. Do not drink beverages while sucking on a nicotine lozenge.
This instruction is correct because when using nicotine lozenges, the client should not drink beverages while the lozeng is being dissolved in the mouth. The lozenge should be placed in the mouth and allowed to dissolve slowly over a period of about 20-30 minutes. Consuming beverages can wash away the nicotine from the lozenge too quickly, reducing its effectiveness.
C. Chew nicotine gum for 10 min before spitting it out: Nicotine gum should be chewed for a specific time period (about 30 minutes) until the nicotine is released, and then it should be parked between the cheek and gum until the taste fades, at which point it can be chewed again.
D. Change the nicotine patch every other day: Nicotine patches are usually changed daily, and the site of application should be rotated to avoid skin irritation.
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