A nurse is teaching a client who has rheumatoid arthritis about taking methotrexate. Which of the following information should the nurse include?
Take an antiemetic 1 hr following administration.
Take the medication with an NSAID.
Drink 2 to 3 L Of water per day.
Rinse mouth 2 times per day with an alcohol-based mouthwash.
The Correct Answer is C
Methotrexate causes hyperuricemia which may predispose to kidney stones. Adequate hydration help flush out the uric acid preventing stone formation
A-Although methotrexate can cause nausea and vomiting, this does not always happen, therefore, no need for the antiemetic before intake
B-Taking methotrexate with an NSAID increases risk of gastrointestinal irritation
D-Methotrexate cause stomatitis which may be aggravated by use of alcohol-based mouth wash
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Cimetidine inhibits the cytochrome enzymes leading to increased blood concentration of other drugs like theophylline hence increased risk of toxicity. The dosage of the drugs should be lowered when one is on cimetidine.
A-Cimetidine should be taken with meals or at bedtime for more effective absorption and optimal therapeutic effect.
B. There is no specific duration mentioned for the treatment of duodenal ulcer with cimetidine.
D. Taking cimetidine with an antacid is not recommended as they decrease the absorption of cimetidine.
Correct Answer is A
Explanation
Levodopa/carbidopa is metabolized to dopamine in the brain. This increases concentration of dopamine in the brain to bind dopaminergic neurons hence promoting cognition and motor movements in Parkinson disease
B. Piperacillin/tazobactam is an antibiotic used to manage bacterial infections.
C. Carbamazepine- is an anticonvulsant agent used in seizures control and other psychiatric illnesses.
D. Levothyroxine-a synthetic thyroid hormone used in the management of hypothyroidism.
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