A nurse is teaching a client who has rheumatoid arthritis about taking methotrexate. Which of the following information should the nurse include?
Take an antiemetic 1 hr following administration.
Take the medication with an NSAID.
Drink 2 to 3 L Of water per day.
Rinse mouth 2 times per day with an alcohol-based mouthwash.
The Correct Answer is C
Methotrexate causes hyperuricemia which may predispose to kidney stones. Adequate hydration help flush out the uric acid preventing stone formation
A-Although methotrexate can cause nausea and vomiting, this does not always happen, therefore, no need for the antiemetic before intake
B-Taking methotrexate with an NSAID increases risk of gastrointestinal irritation
D-Methotrexate cause stomatitis which may be aggravated by use of alcohol-based mouth wash
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Warfarin is a coumarin anticoagulant that has potential to increase the risk of bleeding. When taken during pregnancy, warfarin causes fetal bleeding. Warfarin is also teratogenic and it causes various birth defects including skeletal abnormalities, hypoplastic nose, intellectual disabilities and deafness hence it's contraindicated. Pregnant women who require anticoagulation are put of heparin in the place of warfarin to prevent these complications.
A. B, D - are not contraindications for warfarin use.
Correct Answer is B
Explanation
A. Diluting phenytoin with sterile water before injecting is not recommended, as phenytoin is incompatible with most used diluents. Diluting it can lead to precipitation and potentially cause adverse effects such as tissue irritation and phlebitis.
B. Administering the medication over 1 min is recommended. Phenytoin should be administered at a rate of 50mg/min.
C. Following the IV injection with sterile water is unnecessary and not indicated for administering phenytoin.
D.Phenytoin precipitates out of solution when mixed with certain diluents or when administered too quickly. Crystallized phenytoin can cause local irritation, tissue damage, and potentially more serious adverse effects. Therefore, it should not be administered at all.
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