A nurse is teaching a client who has rheumatoid arthritis about taking methotrexate. Which of the following information should the nurse include?

Take an antiemetic 1 hr following administration.

Take the medication with an NSAID.

Drink 2 to 3 L Of water per day.

Rinse mouth 2 times per day with an alcohol-based mouthwash.

Answer and Explanation

The Correct Answer is C

Methotrexate causes hyperuricemia which may predispose to kidney stones. Adequate hydration help flush out the uric acid preventing stone formation
A-Although methotrexate can cause nausea and vomiting, this does not always happen, therefore, no need for the antiemetic before intake
B-Taking methotrexate with an NSAID increases risk of gastrointestinal irritation
D-Methotrexate cause stomatitis which may be aggravated by use of alcohol-based mouth wash

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Correct Answer is B

Explanation

Montelukast is a leukotriene receptor antagonist used in the management of asthma and allergic rhinitis. Though rare, montelukast can cause neuropsychiatric adverse effects such as including depression, agitation and suicidal behaviors.
A, C, D- are not typically associated with use of montelukast

A. Activated partial thromboplastin time (APTT) B. Bleeding time C. Prothrombin time (PT) D. Hemoglobin (Hgb)

Correct Answer is C

Explanation

warfarin inhibits vitamin K epoxide reductase interfering with the synthesis of vitamin K dependent clotting factors (II, VII, IX, and X). This prolongs the prothrombin time, expressed in the form of INR international normalized ratio. Monitoring of INR helps to ensure that the prescribed dosages are within the therapeutic levels without increasing the risk of bleeding. The target INR range is between 2.5 and 3.5.
A. Used to monitor heparin therapy

B, D- not used for monitoring

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A nurse is teaching a client who has rheumatoid arthritis about taking methotrexate. Which of the following information should the nurse include?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is providing discharge instructions to a client Who has asthma and a new prescription for montelukast. The nurse should instruct the client to report Which of the following adverse effects to the provider?

Correct Answer is B

Explanation

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Correct Answer is C

Explanation

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