A nurse is teaching a client who is prescribed clopidogrel, an antiplatelet drug, to prevent recurrent stroke. Which of the following statements should the nurse include in the teaching? (Select all that apply.)
“You should avoid taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) while on this medication.”
“You should report any signs of bleeding, such as nosebleeds, bruising, or black stools, to your provider.”
“You should take this medication with food to prevent gastrointestinal upset.”
“You should have your blood pressure checked regularly while on this medication.”
“You should stop taking this medication at least 5 days before any planned surgery.”.
Correct Answer : A,B,E
Clopidogrel is an antiplatelet drug that inhibits the ability of platelets to clump together as part of a blood clot. It is used to prevent recurrent stroke and other cardiovascular events in people who are at high risk.
Choice A is correct because taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) while on clopidogrel can increase the risk of bleeding. These drugs also affect platelet function and can interfere with the action of clopidogrel.
Choice B is correct because bleeding is the most common side effect of clopidogrel. Any signs of bleeding, such as nosebleeds, bruising, or black stools, should be reported to the provider as they may indicate a serious complication.
Choice C is wrong because clopidogrel can be taken with or without food. Taking it with food does not prevent gastrointestinal upset, which is another possible side effect of clopidogrel.
Choice D is wrong because clopidogrel does not affect blood pressure. However, having high blood pressure can increase the risk of stroke and other cardiovascular events, so it is important to have it checked regularly and treated if necessary.
Choice E is correct because clopidogrel should be stopped at least 5 days before any planned surgery. This is to reduce the risk of excessive bleeding during or after the surgery. The provider should be informed about the use of clopidogrel and any other medications before undergoing any surgical procedure.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B","E"]
Explanation
Clopidogrel is an antiplatelet drug that inhibits the ability of platelets to clump together as part of a blood clot.It is used to prevent recurrent stroke and other cardiovascular events in people who are at high risk.
Choice A is correct because taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) while on clopidogrel can increase the risk of bleeding.These drugs also affect platelet function and can interfere with the action of clopidogrel.
Choice B is correct because bleeding is the most common side effect of clopidogrel.Any signs of bleeding, such as nosebleeds, bruising, or black stools, should be reported to the provider as they may indicate a serious complication.
Choice C is wrong because clopidogrel can be taken with or without food.Taking it with food does not prevent gastrointestinal upset, which is another possible side effect of clopidogrel.
Choice D is wrong because clopidogrel does not affect blood pressure.However, having high blood pressure can increase the risk of stroke and other cardiovascular events, so it is important to have it checked regularly and treated if necessary.
Choice E is correct because clopidogrel should be stopped at least 5 days before any planned surgery.This is to reduce the risk of excessive bleeding during or after the surgery.The provider should be informed about the use of clopidogrel and any other medications before undergoing any surgical procedure.
Correct Answer is A
Explanation
Omeprazole, a proton pump inhibitor, is contraindicated with cilostazol, an antiplatelet drug, for intermittent claudication.
This is because omeprazole can inhibit the metabolism of cilostazol by affecting the hepatic/intestinal enzyme CYP2C19, which is responsible for converting cilostazol to its active metabolites.This can result in increased plasma levels of cilostazol and increased risk of bleeding and adverse effects.
Choice B is wrong because metoprolol, a beta blocker, is not contraindicated with cilostazol.
Metoprolol can be used to treat hypertension, angina, and heart failure, which are common comorbidities in patients with intermittent claudication.Metoprolol does not interact significantly with cilostazol or affect its metabolism.
Choice C is wrong because simvastatin, a statin, is not contraindicated with cilostazol.
Simvastatin can be used to lower cholesterol and prevent cardiovascular events in patients with intermittent claudication.Simvastatin does not interact significantly with cilostazol or affect its metabolism.
Choice D is wrong because glyburide, a sulfonylurea, is not contraindicated with cilostazol.
Glyburide can be used to treat type 2 diabetes mellitus, which is a common risk factor for intermittent claudication.Glyburide does not interact significantly with cilostazol or affect its metabolism.
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