A nurse is teaching a female client who is to start taking atorvastatin. Which of the following baseline examinations should the nurse include?
Liver function tests.
Thyroid function tests.
Renal function tests.
Blood glucose tests.
The Correct Answer is A
Choice A reason: Atorvastatin, a statin, inhibits HMG-CoA reductase, reducing cholesterol synthesis in the liver. It can elevate liver enzymes (ALT, AST), indicating hepatotoxicity. Baseline liver function tests are essential to assess hepatic health before starting therapy, ensuring no pre-existing liver damage and monitoring for drug-induced liver injury during treatment.
Choice B reason: Thyroid function tests assess thyroid hormone levels, relevant for conditions like hypothyroidism, which can elevate lipids. Atorvastatin does not directly affect thyroid function or metabolism, so these tests are not routinely required before starting therapy unless thyroid disease is suspected as a contributor to hyperlipidemia.
Choice C reason: Renal function tests monitor kidney health, critical for drugs cleared renally. Atorvastatin is primarily metabolized by the liver via cytochrome P450 3A4, not excreted by kidneys. While statins may rarely cause rhabdomyolysis affecting kidneys, baseline renal tests are not mandatory unless renal disease is suspected.
Choice D reason: Blood glucose tests are relevant for diabetes management. Atorvastatin may slightly increase glucose levels, but this is a minor, long-term effect. Baseline glucose testing is not required unless diabetes is suspected. Liver function is the primary concern due to the drug’s hepatic metabolism and potential hepatotoxicity.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Discarding the first void at the start of a 24-hour urine collection ensures the collection begins with urine produced within the exact 24-hour period. This standardizes the sample, capturing all urine produced thereafter, allowing accurate measurement of renal function, hormone levels, or other analytes over a full day.
Choice B reason: Discarding the last void at the end of the 24-hour period is incorrect, as all urine produced within the 24 hours, including the final void, must be collected. Excluding the last void would result in an incomplete sample, skewing results for tests like creatinine clearance or protein excretion.
Choice C reason: Pouring urine into a clean container is incorrect, as 24-hour urine collections require a specialized container with preservatives to maintain sample integrity. Using a clean but non-designated container risks contamination or degradation of analytes, compromising the accuracy of tests like electrolyte or hormone measurements.
Choice D reason: Instructing the client not to void at the end of the collection period is incorrect, as all urine within the 24-hour timeframe, including the final void, must be collected. Missing the last void reduces the total volume, leading to inaccurate results for diagnostic tests evaluating renal or metabolic function.
Correct Answer is ["A","B","C","D","E"]
Explanation
Choice A reason: Documenting the client’s response to interventions, such as medication or positional changes, is critical for evaluating treatment efficacy and guiding care. This includes noting changes in blood pressure or symptoms post-intervention, ensuring continuity of care. Accurate records support clinical decision-making and reflect the physiological impact of interventions on the cardiovascular system.
Choice B reason: Interventions implemented, such as administering antihypertensives or fluids, must be documented to track actions taken in response to blood pressure readings. This ensures a clear record of care provided, facilitating communication among healthcare providers and enabling evaluation of treatment effectiveness in managing the client’s cardiovascular status.
Choice C reason: The frequency of blood pressure measurements is essential to document, as it indicates monitoring intensity based on the client’s condition. For example, unstable patients may require frequent checks. This information ensures consistency in care, tracks trends in cardiovascular status, and supports timely interventions for abnormal readings.
Choice D reason: The client’s position (e.g., sitting, lying, standing) during blood pressure measurement affects readings due to gravitational effects on blood flow. Documenting position ensures accurate interpretation of results, as orthostatic changes can indicate hypovolemia or autonomic dysfunction. This detail is critical for assessing cardiovascular stability and guiding treatment plans.
Choice E reason: The site of blood pressure measurement (e.g., arm, wrist, thigh) must be documented, as different sites can yield varying readings due to arterial size and proximity to the heart. Specifying the site ensures consistency in serial measurements and accurate interpretation of cardiovascular status, supporting reliable clinical decision-making.
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