A nurse is teaching a female client who is to start taking atorvastatin. Which of the following baseline examinations should the nurse include?
Liver function tests.
Thyroid function tests.
Renal function tests.
Blood glucose tests.
The Correct Answer is A
Choice A reason: Atorvastatin, a statin, inhibits HMG-CoA reductase, reducing cholesterol synthesis in the liver. It can elevate liver enzymes (ALT, AST), indicating hepatotoxicity. Baseline liver function tests are essential to assess hepatic health before starting therapy, ensuring no pre-existing liver damage and monitoring for drug-induced liver injury during treatment.
Choice B reason: Thyroid function tests assess thyroid hormone levels, relevant for conditions like hypothyroidism, which can elevate lipids. Atorvastatin does not directly affect thyroid function or metabolism, so these tests are not routinely required before starting therapy unless thyroid disease is suspected as a contributor to hyperlipidemia.
Choice C reason: Renal function tests monitor kidney health, critical for drugs cleared renally. Atorvastatin is primarily metabolized by the liver via cytochrome P450 3A4, not excreted by kidneys. While statins may rarely cause rhabdomyolysis affecting kidneys, baseline renal tests are not mandatory unless renal disease is suspected.
Choice D reason: Blood glucose tests are relevant for diabetes management. Atorvastatin may slightly increase glucose levels, but this is a minor, long-term effect. Baseline glucose testing is not required unless diabetes is suspected. Liver function is the primary concern due to the drug’s hepatic metabolism and potential hepatotoxicity.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Medication reconciliation is critical in all healthcare settings, including behavioral health facilities, to prevent errors like drug interactions or omissions. Psychotropic medications often interact via cytochrome P450 enzymes, and skipping reconciliation risks adverse events, especially in patients with complex regimens, ensuring safe transitions across care settings.
Choice B reason: Compiling a current medication list during admission is essential for reconciliation, ensuring continuity of care. It involves verifying home medications against facility orders, identifying discrepancies, and preventing errors like duplications or omissions, particularly for drugs affecting cardiovascular or neurological systems, which require precise management to avoid adverse outcomes.
Choice C reason: Over-the-counter medications must be included in reconciliation, as they can interact with prescribed drugs (e.g., NSAIDs with anticoagulants increase bleeding risk). Excluding them risks incomplete profiles, leading to potential adverse interactions or therapeutic failures, especially since patients often self-administer these without reporting, necessitating thorough documentation.
Choice D reason: Medication history is a core component of reconciliation, providing context for current prescriptions. Excluding it risks missing chronic conditions or past adverse reactions, leading to inappropriate prescribing. For example, a history of beta-blocker use informs cardiovascular management, ensuring safe transitions and preventing errors in polypharmacy scenarios.
Correct Answer is A
Explanation
Choice A reason: Mottled skin, or livedo reticularis, is common at the end of life due to circulatory shutdown. Reduced cardiac output and vasoconstriction in peripheral vessels cause uneven blood flow, leading to mottling. This reflects systemic hypoperfusion as the body prioritizes vital organs in terminal stages.
Choice B reason: Hypertension is uncommon at the end of life, as circulatory failure typically causes hypotension due to decreased cardiac output and vascular tone. Sympathetic drive may briefly elevate blood pressure, but terminal hypoperfusion leads to low pressure, not sustained hypertension, in dying patients.
Choice C reason: Moist mucous membranes are not typical at the end of life, as dehydration occurs from reduced intake and fluid shifts. Dry mucous membranes result from decreased salivary and mucosal secretions, reflecting hypovolemia and reduced glandular function in terminal patients, not moist conditions.
Choice D reason: Increased bowel sounds are not expected at the end of life, as gastrointestinal motility slows due to reduced autonomic function and hypoperfusion. Bowel sounds typically decrease or cease, reflecting ileus or shutdown of digestive processes as the body conserves energy in terminal stages.
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