A nurse is teaching a patient about the common adverse reactions that can occur with his prescribed therapy with cephalosporins.
The nurse determines that the teaching was successful when the patient identifies which of the following?

Choice A rationale:

Administering a combination of drugs in TB treatment is not primarily aimed at preventing the incidence of liver dysfunction. The combination therapy's main objective is to address the complex nature of Mycobacterium tuberculosis infections and the potential development of antibiotic resistance.

Choice B rationale:

The nurse should explain that the primary reason for administering a combination of drugs is to slow down bacterial resistance. When TB is treated with a single drug, the bacteria can quickly develop resistance to that drug. Using a combination of drugs with different mechanisms of action makes it more difficult for the bacteria to develop resistance. This is a fundamental principle in the treatment of TB.

Choice C rationale:

Slowing the body's resistance to medication is not a goal in TB treatment. The focus is on preventing the development of resistance in the bacteria, not the body's response to the medication.

Choice D rationale:

While TB treatment aims to prevent the further spread of the disease, the primary reason for using a combination of drugs is to address bacterial resistance. Preventing the spread of TB is an important secondary benefit of effective treatment.

Choice A rationale:

Macrolides are typically broad-spectrum antibiotics, not narrow-spectrum. They are effective against a wide range of bacteria, making them a valuable option for various infections.

Choice B rationale:

Macrolides are generally well-tolerated, and they are not contraindicated in clients with renal dysfunction. In fact, macrolides like azithromycin are often preferred in such cases due to their minimal renal excretion.

Choice C rationale:

Macrolides, specifically erythromycin, have been associated with ototoxicity, which can lead to hearing impairment. This side effect is relatively rare but can occur, especially with high doses or prolonged use. It's important for healthcare providers to monitor for this potential adverse effect.

Choice D rationale:

Macrolides are often used as an alternative for clients who are allergic to penicillins, so they can be used in this population when appropriate. The cross-reactivity between these drug classes is relatively low, and macrolides can be a suitable choice for penicillin-allergic individuals.