After administering sulfonamides to a client, the nurse observes that he has developed a fever, cough, and muscular aches.
The nurse also observes that the client has developed lesions in the form of red wheals on the neck and the mouth.
The nurse interprets these findings as indicating which of the following?

Choice A rationale:

Administering a combination of drugs in TB treatment is not primarily aimed at preventing the incidence of liver dysfunction. The combination therapy's main objective is to address the complex nature of Mycobacterium tuberculosis infections and the potential development of antibiotic resistance.

Choice B rationale:

The nurse should explain that the primary reason for administering a combination of drugs is to slow down bacterial resistance. When TB is treated with a single drug, the bacteria can quickly develop resistance to that drug. Using a combination of drugs with different mechanisms of action makes it more difficult for the bacteria to develop resistance. This is a fundamental principle in the treatment of TB.

Choice C rationale:

Slowing the body's resistance to medication is not a goal in TB treatment. The focus is on preventing the development of resistance in the bacteria, not the body's response to the medication.

Choice D rationale:

While TB treatment aims to prevent the further spread of the disease, the primary reason for using a combination of drugs is to address bacterial resistance. Preventing the spread of TB is an important secondary benefit of effective treatment.