A nursing instructor is preparing a teaching plan for a group of nursing students about macrolide antibacterial drugs.
Which of the following would the instructor expect to include?
Macrolides are narrow-spectrum antibiotics.
Macrolides are contraindicated in clients with renal dysfunction.
Macrolides may cause hearing impairment.
Macrolides cannot be used in clients allergic to penicillins.
The Correct Answer is C
Choice A rationale:
Macrolides are typically broad-spectrum antibiotics, not narrow-spectrum. They are effective against a wide range of bacteria, making them a valuable option for various infections.
Choice B rationale:
Macrolides are generally well-tolerated, and they are not contraindicated in clients with renal dysfunction. In fact, macrolides like azithromycin are often preferred in such cases due to their minimal renal excretion.
Choice C rationale:
Macrolides, specifically erythromycin, have been associated with ototoxicity, which can lead to hearing impairment. This side effect is relatively rare but can occur, especially with high doses or prolonged use. It's important for healthcare providers to monitor for this potential adverse effect.
Choice D rationale:
Macrolides are often used as an alternative for clients who are allergic to penicillins, so they can be used in this population when appropriate. The cross-reactivity between these drug classes is relatively low, and macrolides can be a suitable choice for penicillin-allergic individuals.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Correct Answer is A
Explanation
Choice A rationale:
Aminoglycosides are known to have nephrotoxic effects. Nephrotoxicity refers to kidney toxicity, and aminoglycosides can cause damage to the renal tubules, leading to impaired kidney function. The nurse should be alert to this potential toxicity when administering these drugs, as it can result in kidney dysfunction, altered serum creatinine levels, and electrolyte imbalances.
Choice B rationale:
Cardiotoxicity is not typically associated with aminoglycosides. These antibiotics primarily affect the kidneys and the inner ear. There is no direct relationship between aminoglycosides and cardiac toxicity.
Choice C rationale:
Hepatotoxicity refers to liver toxicity and is not a common side effect of aminoglycosides. Aminoglycosides are primarily metabolized in the kidneys and are excreted through urine, making kidney toxicity a more significant concern.
Choice D rationale:
Cytotoxicity is a broad term that refers to the toxicity of cells. Aminoglycosides do not typically cause generalized cytotoxic effects in the body. Their primary toxicities are related to specific organ systems, such as the kidneys and the inner ear.
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