A nursing instructor is teaching a group of nursing students about antihistamines. Which statement by a student indicates an understanding of the mechanism of action of the antihistamines?
"Antihistamines block release of histamine from mast cells and basophils."
"Antihistamines block H1 receptors to prevent actions of histamine at these sites."
"H1 antagonists can bind to H1 receptors, H2 receptors, and muscarinic receptors."
"First-generation antihistamines are more selective than second-generation antihistamines."
The Correct Answer is B
Antihistamines primarily work by blocking the H1 receptors, which are the receptors responsible for mediating the actions of histamine in the body. By blocking these receptors, antihistamines prevent or reduce the effects of histamine, such as itching, sneezing, runny nose, and watery eyes. This is the main mechanism by which antihistamines provide their therapeutic effects. "Antihistamines block release of histamine from mast cells and basophils." This statement is incorrect. Antihistamines do not block the release of histamine; instead, they block the histamine receptors to prevent the effects of histamine.
"H1 antagonists can bind to H1 receptors, H2 receptors, and muscarinic receptors." This statement is incorrect. H1 antagonists, or H1 receptor blockers, specifically bind to H1 receptors and do not have significant affinity for H2 receptors or muscarinic receptors. "First-generation antihistamines are more selective than second-generation antihistamines." This statement is incorrect. First-generation antihistamines are generally less selective and can have more sedating and anticholinergic effects compared to second-generation antihistamines, which are designed to be more selective for H1 receptors and have reduced sedative properties.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["B","C","D","G","H"]
Explanation
Low oxygen saturation: Low oxygen saturation indicates a potential respiratory compromise and should be addressed promptly to ensure adequate oxygenation and prevent further deterioration.
Previous injection drug user and alcohol misuse: Past injection drug use and alcohol misuse can have significant implications for the patient's health, including increased risk of infections, compromised immune function, and potential withdrawal symptoms. It is crucial for the nurse to be aware of these factors in order to provide appropriate care and support. Has productive cough severe enough to keep her awake: A severe productive cough that disrupts the patient's sleep suggests respiratory distress or possible worsening of the underlying condition. The nurse should assess the patient's respiratory status and implement interventions to alleviate the cough and improve rest.
Elevated temperature, pulse, and respiratory rate: An elevation in vital signs, including temperature, pulse, and respiratory rate, can indicate an infectious or inflammatory process. This warrants further assessment and intervention to manage the underlying condition. Diagnosis pneumonia: The diagnosis of pneumonia indicates a respiratory infection that requires close monitoring and appropriate treatment. The nurse should assess the patient's respiratory status, administer prescribed medications, and implement respiratory hygiene measures.
The following options are not immediate concerns or relevant assessment information:
Appointment the next day: While follow-up appointments are important, they do not require immediate attention upon receiving a hand-off report.
Marital status: Marital status is not typically an immediate concern for the nurse's assessment and care planning.
Daughter's name: The patient's family member's name is not an immediate concern or relevant assessment information for the nurse's immediate care.
Fever is present: While a fever is a symptom of an underlying condition, it is not the most critical concern.
Correct Answer is A
Explanation
Albuterol is a short-acting beta-agonist bronchodilator that provides rapid relief of bronchospasm and helps to alleviate the symptoms of respiratory distress in asthma. It acts quickly to relax the smooth muscles in the airways, improving airflow and relieving wheezing, coughing, and shortness of breath. In an acute asthma exacerbation, albuterol is often the first-line medication used to provide immediate relief and improve respiratory function. Prednisone is an oral corticosteroid that has anti-inflammatory effects and is commonly used in the treatment of asthma. However, it is typically administered orally and takes time to exert its effects. In the emergency department setting, the focus is on providing immediate relief of symptoms, and oral medications like prednisone may not have an immediate effect. Ipratropium is an anticholinergic bronchodilator that can be administered via inhalation. While it is effective in relieving bronchospasm, it is generally used as an adjunct to albuterol and not typically the first-line medication for severe respiratory distress in asthma. Fluticasone is an inhaled corticosteroid that has anti-inflammatory effects and is used for long-term management and control of asthma. It is not appropriate for immediate relief of severe respiratory distress and is not typically used as a first-line medication in the emergency department.
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