A patient is diagnosed with Hashimoto's thyroiditis. Which clinical manifestations are expected?

A. Diminished serum albumin levels cause water to shift from blood to tissue: In cirrhosis, liver dysfunction leads to decreased production of albumin, a protein that helps maintain oncotic pressure. Low albumin levels cause fluid to shift from the vascular space into the tissues, resulting in ascites and peripheral edema.

B. Portal hypotension causes a fluid shift from the abdominal cavity into the portal veins: Portal hypertension, not hypotension, is a common feature of cirrhosis, but it leads to ascites by increasing pressure in the portal venous system, not by shifting fluid into the portal veins.

C. Hypoaldosteronism causes a fluid volume deficit: shifting water from blood into tissue: Cirrhosis often leads to hyperaldosteronism, not hypoaldosteronism, resulting in sodium and water retention, which contributes to edema.

D. Aberrations of the portal system cause a back-up of blood that leads to hydronephrosis: Hydronephrosis is related to obstruction of the urinary tract, not a complication of portal hypertension or cirrhosis.

A. Steroid injections will be administered daily: This is incorrect; steroid therapy may exacerbate Cushing's disease. The condition is often due to excessive production of cortisol, not a deficiency.

B. Weight gain and edema are present: Hyperaldosteronism, often associated with Cushing's syndrome, leads to sodium and water retention, resulting in weight gain and edema.

C. Painful leg cramps are common from hyperkalemia: Hyperaldosteronism typically causes hypokalemia, not hyperkalemia, leading to muscle cramps, not leg pain from hyperkalemia.

D. Decreased amount of body hair is frequently seen: Cushing's disease often leads to hirsutism (increased body hair), not a decrease.