A patient is taking a monoamine oxidase inhibitor for depression. In planning care for this patient, the nurse knows that a hypertensive crisis may be possible and plans on having what drug on hand as an antidote?
Meperidine (Demerol)
Calcium channel blockers
Carbamazepine (Tegretol)
Dextromethorphan
The Correct Answer is B
A. Meperidine is contraindicated with monoamine oxidase inhibitors (MAOIs) and can lead to serotonin syndrome rather than being an antidote for hypertensive crisis.
B. Calcium channel blockers, such as nifedipine, are commonly used as antidotes for hypertensive crisis associated with MAOI use.
C. Carbamazepine is not indicated for the treatment of hypertensive crisis associated with MAOI use.
D. Dextromethorphan is contraindicated with MAOIs due to the risk of serotonin syndrome.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Verapamil is a calcium channel blocker, not a beta blocker.
B. Captopril is an angiotensin-converting enzyme (ACE) inhibitor, not a beta blocker.
C. Atenolol is a beta blocker commonly used to treat hypertension, angina, and other cardiovascular conditions.
D. Clopidogrel is an antiplatelet medication used to prevent blood clots, not a beta blocker.
Correct Answer is C
Explanation
A. Orange juice does not interact with simvastatin and does not need to be avoided.
B. Coenzyme Q10 (CoQ10) supplements are sometimes taken by patients on statins to help alleviate the side effects like muscle pain, but they do not need to be avoided.
C. Grapefruit juice should be avoided while taking simvastatin because it contains compounds that interfere with the enzymes that metabolize statins, potentially leading to increased drug levels and greater risk of side effects such as muscle damage.
D. Not all fruit juices interact with simvastatin; the specific concern is with grapefruit juice.
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