A patient with a complicated medical history including hypertension, a-fib, and arthritis calls the health care provider's office to speak with a nurse about "all of these bruises I have all of a sudden." Which potential drug interaction should concern the nurse with these symptoms?

Aspirin and warfarin

Sulfasalazine and acetaminophen

Tolmetin and propranolol

Meloxicam and amlodipine

Answer and Explanation

The Correct Answer is A

A. Aspirin and warfarin

The combination of aspirin and warfarin poses a potential risk of increased bleeding and bruising. Both aspirin and warfarin are anticoagulants, and when used together, they can potentiate each other's effects, leading to a higher risk of bleeding events, including easy bruising.

B. Sulfasalazine and acetaminophen

Sulfasalazine is often used in the treatment of arthritis and inflammatory bowel disease, while acetaminophen is a commonly used pain reliever. There is no significant interaction between these two medications leading to increased bleeding or bruising.

C. Tolmetin and propranolol

Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief, and propranolol is a beta-blocker used for conditions such as hypertension. While both medications have their own potential side effects, there is no specific interaction between them that significantly increases the risk of bleeding or bruising.

D. Meloxicam and amlodipine

Meloxicam is an NSAID, and amlodipine is a calcium channel blocker used for hypertension. Similar to option C, there is no known significant interaction between these two medications that would lead to increased bleeding or bruising.

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Correct Answer is ["2.5"]

Explanation

To calculate the amount of solution needed for each dose, we need to use the formula:

Amount of solution (mL) = Dose (mg) / Concentration (mg/mL)

Plugging in the given values, we get:

Amount of solution (mL) = 50 mg / 20 mg/mL

Simplifying, we get:

Amount of solution (mL) = 2.5 mL

Therefore, the nurse must administer 2.5 mL of the solution for each dose.

A. "Continue taking OCPS because phenytoin is not safe during pregnancy." B. "You should use a backup method of contraception along with OCPs." C. "You should stop taking OCPs because of drug-drug interactions with phenytoin." D. "You should take low-dose aspirin while taking these medications to reduce your risk of stroke."

Correct Answer is B

Explanation

A. "Continue taking OCPS because phenytoin is not safe during pregnancy."

This statement is not accurate. While it's essential to address pregnancy risk, phenytoin can reduce the effectiveness of oral contraceptives. Women on phenytoin are often advised to use additional contraceptive measures.

B. "You should use a backup method of contraception along with OCPs."

This is the correct response. Phenytoin can accelerate the metabolism of oral contraceptives, potentially reducing their effectiveness. Using a backup method, such as condoms, is recommended to ensure adequate contraception.

C. "You should stop taking OCPs because of drug-drug interactions with phenytoin."

This advice is generally not recommended without consulting the healthcare provider. Abruptly stopping OCPs without an alternative form of contraception can increase the risk of unintended pregnancy.

D. "You should take low-dose aspirin while taking these medications to reduce your risk of stroke."

This statement is not relevant to the situation described. Low-dose aspirin is not typically recommended for contraception, and its use in this context does not address the potential interaction between phenytoin and oral contraceptives.

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A patient with a complicated medical history including hypertension, a-fib, and arthritis calls the health care provider's office to speak with a nurse about "all of these bruises I have all of a sudden." Which potential drug interaction should concern the nurse with these symptoms?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A health care provider prescribes 50 mg of a drug. The drug is only available in a 20 mL vial that contains 20 mg/mL of the drug. How much solution must the nurse administer for each dose?

Correct Answer is ["2.5"]

Explanation

A 25 year-old female patient will begin taking phenytoin for epilepsy. The patient tells the nurse she is taking oral contraceptives (OCPs). Which response will the nurse give?

Correct Answer is B

Explanation

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