A patient with alcoholic liver disease has severe anemia. Which of the following explains the development of anemia in this particular patient?
Alcohol suppresses erythropoiesis.
Alcoholics are often deficient in folate.
Liver dysfunction leads to decreased clotting factors.
Gastric ulcers may lead to chronic blood loss.
Alcohol causes inflammation, which leads to anemia.
The Correct Answer is A
A. Alcohol can directly suppress the production of red blood cells (erythropoiesis) in the bone marrow, leading to anemia.
B. While alcoholics may indeed be deficient in folate due to poor nutrition, folate deficiency is not the primary mechanism for anemia in alcoholic liver disease.
C. Liver dysfunction can lead to decreased production of clotting factors, contributing to coagulopathy, but it is not the primary mechanism for anemia in alcoholic liver disease.
D. Gastric ulcers may indeed lead to chronic blood loss, contributing to anemia, but it is not specific to alcoholic liver disease.
E. While alcohol-induced inflammation may contribute to various complications, including liver damage, it is not the primary mechanism for anemia in alcoholic liver disease.
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Related Questions
Correct Answer is C
Explanation
A. Vitamin C is not known to cause bone marrow suppression. In fact, it is essential for the proper function of the immune system and the production of collagen.
B. Physical exercise does not cause bone marrow suppression. Regular exercise can have positive effects on bone health and overall well-being.
C. Chemotherapy, which is used to treat cancer, can cause bone marrow suppression as a side effect. It affects rapidly dividing cells, including those in the bone marrow responsible for producing blood cells.
D. Some antibiotics, such as certain types of penicillins and sulfonamides, can rarely cause bone marrow suppression as a side effect. However, this is not a common effect of all antibiotics.
Correct Answer is D
Explanation
A. Total protein level. Total protein level does not directly indicate bone marrow suppression.
B. Serum potassium level. Serum potassium level reflects electrolyte balance but is not specific for bone marrow suppression.
C. Erythrocyte sedimentation rate (ESR). ESR can indicate inflammation but is not a reliable indicator of bone marrow suppression.
D. Platelet count. Platelet count is a reliable indicator of bone marrow suppression because chemotherapy can significantly reduce platelet production, leading to thrombocytopenia.
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