Which laboratory test will the nurse use to determine whether filgrastim (Neupogen) is effective for a patient with acute lymphocytic leukemia who is receiving chemotherapy?
Reticulocyte count
White blood count / Absolute neutrophil count
Total lymphocyte count
Platelet count
The Correct Answer is B
A. Reticulocyte count: Reticulocyte count measures immature red blood cells and is not the primary measure for the effectiveness of filgrastim, which is used to boost white blood cells.
B. White blood count / Absolute neutrophil count: Filgrastim (Neupogen) is used to increase white blood cells, specifically neutrophils. Therefore, monitoring the white blood count (WBC) and absolute neutrophil count (ANC) is the appropriate way to determine the effectiveness of the drug.
C. Total lymphocyte count: While lymphocytes are a type of white blood cell, filgrastim primarily affects neutrophils, making WBC/ANC a better indicator.
D. Platelet count: Filgrastim does not directly impact platelet production, so platelet count is not the primary measure of its effectiveness.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Syphilis can indeed affect many areas of the body, including the brain and heart, but this statement does not specifically address primary syphilis, which is characterized by the appearance of a painless sore (chancre) at the site of infection.
B. Syphilis does not typically resolve on its own. Without treatment, the infection can progress to more severe stages with potentially serious complications.
C. Syphilis is caused by a bacterial infection (Treponema pallidum) and is treated with antibiotics such as penicillin. Antiviral medications are not effective against bacterial infections like syphilis.
D. This statement is accurate and important for the prevention of syphilis transmission. Syphilis can be transmitted through vaginal, anal, or oral sex, but the risk of transmission is lower during oral sex compared to vaginal or anal intercourse.
Correct Answer is A
Explanation
A. This response accurately describes the pathophysiology of sickle cell crisis. During a crisis, sickled red blood cells clump together, leading to microvascular occlusion and impaired blood flow to tissues, resulting in pain.
B. Bleeding in the joints is not a characteristic feature of sickle cell crisis. It may occur in other conditions such as hemophilia or osteoarthritis but not in sickle cell crisis.
C. Disturbance in cellular metabolism is not the primary mechanism underlying the pain experienced during sickle cell crisis.
D. Bone marrow expansion with sickled cells may contribute to bone pain in sickle cell disease, but it is not the primary cause of pain during a sickle cell crisis.
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