A patient with neuroleptic malignant syndrome has been prescribed dantrolene 1.5 mg/kg IV. The patient weighs 132 pounds.
The label on the 250 mg vial reads, “Reconstitute with 5 mL sterile water for injection, USP. Reconstitution yields 50 mg/mL.”. How many mL should the nurse administer?
The Correct Answer is ["1.80"]
Step 1 is to convert the patient’s weight from pounds to kilograms since the dosage is prescribed in mg/kg. We know that 1 kg is approximately 2.20462 pounds. So, the patient’s weight in kilograms is 132 pounds ÷ 2.20462 = 59.87 kg.
Step 2 is to calculate the total dosage of dantrolene needed. The prescribed dosage is 1.5 mg/kg. So, the total dosage is 1.5 mg/kg × 59.87 kg = 89.81 mg.
Step 3 is to calculate the volume of reconstituted dantrolene solution needed to provide the total dosage. The reconstituted solution has a concentration of 50 mg/mL. So, the volume needed is 89.81 mg ÷ 50 mg/mL = 1.80 mL.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale
Moon facies, characterized by a round face, is a side effect of long-term use of prednisone. However, it is not the most important symptom for the client to report to the healthcare provider in this context.
Choice B rationale
Abdominal striae, or stretch marks on the abdomen, can also be a side effect of long-term use of prednisone. While it may be a concern for some patients due to cosmetic reasons, it is not the most critical symptom to report in this case.
Choice C rationale
Gastric irritation is a common side effect of prednisone and can lead to more serious complications such as gastric ulcers if not addressed promptly. Therefore, it is the most important symptom for the client to report to the healthcare provider.
Choice D rationale
Rapid weight gain can be a side effect of prednisone use. While it is important to monitor weight while on this medication, it is not the most critical symptom to report in comparison to gastric irritation.
Correct Answer is D
Explanation
Choice A rationale
Ceasing the use of the nasal cannula would interrupt the client’s oxygen therapy, which could potentially worsen their condition. Therefore, this is not the best course of action.
Choice B rationale
Reducing the flow rate to 1 L/minute may not be appropriate as the client’s oxygen needs may not be met at a lower flow rate. The redness under the chin is likely due to the friction from the cannula tubing, not the flow rate of the oxygen.
Choice C rationale
Applying lubricant to the cannula tubing may not be effective in preventing skin breakdown and could potentially cause additional discomfort or complications for the client.
Choice D rationale
Attaching padding around the cannula tubing can help reduce the friction between the tubing and the skin, which can help prevent skin breakdown. This is the most appropriate action to take in this situation.
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