A patient with renal impairment is prescribed a medication that is primarily excreted by the kidneys. What adjustment should the nurse anticipate?

Administering the medication with meals only

No dose adjustment is required

Increasing the dose to ensure therapeutic effect

Decreasing the dose to prevent toxicity

Answer and Explanation

The Correct Answer is D

Choice A reason: Administering the medication with meals only is not a valid adjustment for a medication that is primarily excreted by the kidneys. The food intake does not affect the renal clearance of the drug, unless it alters the pH of the urine or the blood flow to the kidneys. The nurse should follow the instructions on the medication label or the prescriber's order regarding the timing of the administration.

Choice B reason: No dose adjustment is required is an incorrect statement for a medication that is primarily excreted by the kidneys. The renal impairment can reduce the elimination of the drug and increase its concentration in the blood. This can cause adverse effects and toxicity. The nurse should consult with the prescriber or the pharmacist about the appropriate dose reduction or frequency change for the patient's level of renal function.

Choice C reason: Increasing the dose to ensure therapeutic effect is a dangerous and inappropriate adjustment for a medication that is primarily excreted by the kidneys. The renal impairment can reduce the elimination of the drug and increase its concentration in the blood. This can cause adverse effects and toxicity. The nurse should not increase the dose without the prescriber's order and should monitor the patient for signs of overdose or toxicity.

Choice D reason: Decreasing the dose to prevent toxicity is the correct and rational adjustment for a medication that is primarily excreted by the kidneys. The renal impairment can reduce the elimination of the drug and increase its concentration in the blood. This can cause adverse effects and toxicity. The nurse should consult with the prescriber or the pharmacist about the appropriate dose reduction or frequency change for the patient's level of renal function. The nurse should also monitor the patient for the therapeutic response and the adverse effects of the drug.

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Correct Answer is D

Explanation

Choice A reason: This is incorrect. Aspirin can be used to relieve headache, but that is not its main function in this context. Aspirin is prescribed to patients who have had a heart attack to reduce the risk of another one.

Choice B reason: This is incorrect. Aspirin can be used to reduce fever, but that is not its main function in this context. Aspirin is prescribed to patients who have had a heart attack to reduce the risk of another one.

Choice C reason: This is incorrect. Aspirin does not act as an antiviral. It has no effect on viral infections. Aspirin is prescribed to patients who have had a heart attack to reduce the risk of another one.

Choice D reason: This is correct. Aspirin prevents further clot formation by inhibiting the activity of platelets, which are blood cells that help form clots. Clots can block the blood flow to the heart and cause a heart attack. Aspirin reduces the chance of this happening by making the blood less sticky.

A. 3% sodium chloride B. Dextrose 10% in water C. Lactated Ringer's D. 0.9% sodium chloride

Correct Answer is B

Explanation

Choice A reason: 3% sodium chloride is a hypertonic solution that can cause fluid shifts and dehydration. It is not a suitable replacement for TPN, which is also hypertonic but provides calories, electrolytes, vitamins, and minerals. Infusing 3% sodium chloride can lead to hypernatremia, increased intracranial pressure, and cellular damage.

Choice B reason: Dextrose 10% in water is a hypertonic solution that can provide some calories and prevent hypoglycemia. It is the best option among the choices to replace TPN temporarily, until the new container arrives. However, it does not provide adequate nutrition or electrolytes, so it should not be used for a long time.

Choice C reason: Lactated Ringer's is an isotonic solution that can maintain fluid balance and electrolytes. It is not a suitable replacement for TPN, which is hypertonic and provides more calories and nutrients. Infusing Lactated Ringer's can lead to fluid overload, hyponatremia, and metabolic alkalosis.

Choice D reason: 0.9% sodium chloride is an isotonic solution that can maintain fluid balance and sodium levels. It is not a suitable replacement for TPN, which is hypertonic and provides more calories and nutrients. Infusing 0.9% sodium chloride can lead to fluid overload, hyponatremia, and metabolic acidosis.

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A patient with renal impairment is prescribed a medication that is primarily excreted by the kidneys. What adjustment should the nurse anticipate?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

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Correct Answer is D

Explanation

Correct Answer is B

Explanation

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