A patient with renal impairment is prescribed a medication that is primarily excreted by the kidneys. What adjustment should the nurse anticipate?

Choice A reason: This is incorrect. SQ (subcutaneous) administration involves injecting a drug into the fatty tissue under the skin. This route is slower than IV or IM administration, as the drug has to diffuse through the tissue before reaching the bloodstream.

Choice B reason: This is incorrect. PO (by mouth) administration involves swallowing a drug and absorbing it through the digestive system. This route is the slowest of all, as the drug has to pass through the stomach and the liver before reaching the bloodstream. The drug may also be affected by the first pass effect, which reduces its bioavailability.

Choice C reason: This is correct. IV (intravenous) administration involves injecting a drug directly into a vein. This route is the fastest of all, as the drug enters the bloodstream immediately and reaches the target site quickly. The drug also has 100% bioavailability, meaning none of it is lost or degraded.

Choice D reason: This is incorrect. IM (intramuscular) administration involves injecting a drug into a muscle. This route is faster than SQ or PO administration, as the drug can be absorbed by the capillaries in the muscle. However, it is still slower than IV administration, as the drug has to cross the muscle membrane before reaching the bloodstream.

Choice A reason: This is correct. Blood pressure is the most important vital sign to monitor after giving sublingual nitroglycerin to a client with chest pain. Nitroglycerin is a medication that dilates the blood vessels and lowers the blood pressure. This can relieve the chest pain caused by angina, which is a condition where the heart muscle does not get enough oxygen due to narrowed or blocked arteries. However, if the blood pressure drops too low, the client may experience dizziness, fainting, or shock. Therefore, the nurse should check the blood pressure before and after giving nitroglycerin and report any significant changes to the doctor.

Choice B reason: This is incorrect. Blood glucose levels are not directly affected by sublingual nitroglycerin. However, some clients with chest pain may also have diabetes, which is a risk factor for heart disease. Diabetes is a condition where the body cannot regulate the amount of sugar in the blood. High or low blood sugar levels can cause symptoms such as thirst, hunger, fatigue, blurred vision, or confusion. Therefore, the nurse should check the blood glucose levels of clients with diabetes and follow the doctor's orders for managing their blood sugar.

Choice C reason: This is incorrect. Body temperature is not directly affected by sublingual nitroglycerin. However, some clients with chest pain may also have a fever, which is a sign of infection or inflammation. Fever is a condition where the body's temperature rises above the normal range. Fever can cause symptoms such as sweating, chills, headache, or muscle ache. Therefore, the nurse should check the body temperature of clients with fever and follow the doctor's orders for treating their infection or inflammation.

Choice D reason: This is incorrect. Respiratory rate is not directly affected by sublingual nitroglycerin. However, some clients with chest pain may also have difficulty breathing, which is a sign of heart failure or lung disease. Difficulty breathing is a condition where the client cannot get enough air into or out of the lungs. Difficulty breathing can cause symptoms such as coughing, wheezing, or gasping. Therefore, the nurse should check the respiratory rate of clients with difficulty breathing and follow the doctor's orders for improving their oxygenation.