All of the following are third generation antipsychotics except,
lurasidone (Latuda)
cariprazine (Vraylar)
haloperidol (Haldol)
aripiprazole (Abilify)
The Correct Answer is C
A. Lurasidone (Latuda) is a second-generation (atypical) antipsychotic, not a third-generation antipsychotic. It primarily blocks dopamine (D2) and serotonin (5-HT2A) receptors and is used to treat schizophrenia and bipolar depression.
B. Cariprazine (Vraylar) is a third-generation antipsychotic, functioning as a partial dopamine (D2/D3) and serotonin (5-HT1A) receptor agonist. It is used for schizophrenia, bipolar disorder, and major depressive disorder (MDD) adjunctive treatment.
C. Haloperidol (Haldol) is a first-generation (typical) antipsychotic, not a third-generation antipsychotic. It works by strongly blocking D2 receptors, leading to a high risk of extrapyramidal symptoms (EPS) but lower metabolic side effects compared to atypical antipsychotics.
D. Aripiprazole (Abilify) is a third-generation antipsychotic, known for its partial dopamine (D2) agonist properties. It has a lower risk of EPS and metabolic side effects compared to second-generation antipsychotics and is used for schizophrenia, bipolar disorder, and adjunctive treatment in depression.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Fear of rejection. Individuals with avoidant personality disorder (AVPD) have an intense fear of rejection or criticism, leading them to avoid social situations, relationships, and new experiences despite wanting social connection. This fear stems from deep feelings of inadequacy.
B. Jealous of others. Jealousy is not a defining trait of AVPD but is more commonly associated with narcissistic or borderline personality disorders. People with AVPD are more self-critical and insecure rather than envious of others’ success or relationships.
C. Afraid to make new relationships. Those with AVPD struggle to form new relationships due to fear of embarrassment, criticism, or social failure. They often require strong reassurance and validation before feeling comfortable in social settings.
D. Avoids social interactions. Avoidance of social interactions is a hallmark of AVPD, as individuals tend to withdraw from work, friendships, and social activities to protect themselves from perceived humiliation or failure.
Correct Answer is C
Explanation
A. Clozapine (Clozaril) does not require food for absorption, but it has a high risk of sedation, weight gain, and metabolic side effects. It also requires regular blood monitoring due to the risk of agranulocytosis.
B. Aripiprazole (Abilify) can be taken with or without food, as food does not significantly affect its absorption. It is a partial dopamine agonist, associated with a lower risk of weight gain and metabolic issues compared to other atypical antipsychotics.
C. Lurasidone (Latuda) must be taken with at least 350 calories of food to ensure proper absorption. Taking it on an empty stomach reduces its bioavailability, making it less effective. It is considered a weight-neutral antipsychotic and has a lower risk of metabolic side effects.
D. Haloperidol (Haldol) does not require food for absorption. It is a first-generation antipsychotic (FGA) with a high risk of extrapyramidal symptoms (EPS) but minimal metabolic effects.
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