All of the following are third generation antipsychotics except,
lurasidone (Latuda)
cariprazine (Vraylar)
haloperidol (Haldol)
aripiprazole (Abilify)
The Correct Answer is C
A. Lurasidone (Latuda) is a second-generation (atypical) antipsychotic, not a third-generation antipsychotic. It primarily blocks dopamine (D2) and serotonin (5-HT2A) receptors and is used to treat schizophrenia and bipolar depression.
B. Cariprazine (Vraylar) is a third-generation antipsychotic, functioning as a partial dopamine (D2/D3) and serotonin (5-HT1A) receptor agonist. It is used for schizophrenia, bipolar disorder, and major depressive disorder (MDD) adjunctive treatment.
C. Haloperidol (Haldol) is a first-generation (typical) antipsychotic, not a third-generation antipsychotic. It works by strongly blocking D2 receptors, leading to a high risk of extrapyramidal symptoms (EPS) but lower metabolic side effects compared to atypical antipsychotics.
D. Aripiprazole (Abilify) is a third-generation antipsychotic, known for its partial dopamine (D2) agonist properties. It has a lower risk of EPS and metabolic side effects compared to second-generation antipsychotics and is used for schizophrenia, bipolar disorder, and adjunctive treatment in depression.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Aripiprazole (Abilify) is a second-generation (atypical) antipsychotic with a lower risk of extrapyramidal symptoms (EPS) due to its partial dopamine agonist mechanism. It has a lower incidence of tardive dyskinesia and dystonia compared to typical antipsychotics.
B. Clozapine (Clozaril) has the lowest risk of EPS among antipsychotics because it weakly blocks D2 receptors and primarily targets serotonin (5-HT2A) receptors. However, it carries a high risk of agranulocytosis, sedation, and metabolic syndrome.
C. Lurasidone (Latuda) is a second-generation antipsychotic with a moderate risk of EPS, particularly akathisia (restlessness). However, it has a lower risk than first-generation (typical) antipsychotics like haloperidol.
D. Haloperidol (Haldol) is a first-generation (typical) antipsychotic with a high risk of EPS due to its strong dopamine (D2) receptor blockade. It is associated with dystonia, akathisia, parkinsonism, and tardive dyskinesia, making it the antipsychotic with the highest EPS risk in this list.
Correct Answer is C
Explanation
A. Only engages in solitary activities. Individuals with schizoid personality disorder (SPD) prefer solitary activities and show little interest in social interactions. They are emotionally detached and lack the desire for close relationships, including friendships and romantic partnerships.
B. Dislikes criticism. While people with SPD may be indifferent to praise or criticism, they are not particularly sensitive to it. Unlike avoidant personality disorder, where individuals avoid social interactions due to fear of rejection, those with SPD are emotionally detached and often indifferent to others' opinions.
C. Always wants to be center of attention. This describes histrionic personality disorder (HPD), not schizoid personality disorder. Individuals with HPD seek constant attention, approval, and validation, whereas those with SPD prefer to remain isolated and avoid social engagement.
D. Affective flattening. Affective flattening (emotional coldness or limited emotional expression) is a key feature of SPD. Individuals display minimal facial expressions, monotone speech, and reduced nonverbal communication, contributing to their perceived social aloofness.
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