An adult client with a closed head injury was admitted to the intensive care unit (ICU) one hour ago following a motor vehicle collision. The client's telemetry displays normal sinus rhythm. After placing an intraventricular cannula for intracranial pressure monitoring, the healthcare provider (HCP) prescribes protocols for IV infusions of mannitol and dopamine. Which nursing intervention has the highest priority?

A. Promote oxygenation to tissues. Oxygenation is not a primary goal in DKA management unless there is a coexisting condition causing hypoxia. DKA primarily leads to metabolic acidosis and dehydration rather than respiratory failure, and oxygenation is typically maintained unless complications such as pneumonia or severe shock develop.
B. Reverse dehydration. Severe dehydration occurs in DKA due to osmotic diuresis caused by hyperglycemia. The priority is to restore intravascular volume with isotonic IV fluids such as 0.9% normal saline to improve circulation, support kidney function, and prevent shock. Fluid replacement is essential for stabilizing blood pressure and promoting glucose clearance.
C. Replace insulin. The lack of insulin is the primary cause of DKA, leading to unchecked lipolysis and ketone production. IV insulin therapy is necessary to suppress ketogenesis, lower blood glucose levels, and allow cells to use glucose for energy. Insulin must be administered cautiously with continuous monitoring to prevent hypoglycemia and electrolyte imbalances.
D. Correct electrolytes that are out of normal range. Electrolyte imbalances, particularly potassium depletion, are common in DKA due to osmotic losses and shifting caused by insulin therapy. Potassium replacement is required even if levels appear normal initially, as insulin will drive potassium into cells, leading to hypokalemia. Sodium and bicarbonate levels should also be monitored and corrected as needed.
E. Provide respiratory support. Respiratory support is not typically required unless the client experiences severe respiratory distress or altered mental status. Kussmaul respirations are a natural compensatory mechanism that helps the body exhale CO₂ and correct acidosis. Supplemental oxygen is only necessary if there is an underlying pulmonary condition or respiratory failure.
F. Prevent hyperventilation. Hyperventilation in the form of Kussmaul respirations is the body's way of compensating for metabolic acidosis. It should not be suppressed, as it plays a crucial role in reducing acid buildup. Treating the underlying cause of DKA with fluids, insulin, and electrolyte replacement will allow respiratory function to normalize.

A. Respiratory rate of 26 breaths/minute. A respiratory rate ≥22 breaths/minute meets the SIRS criteria and indicates systemic inflammation or respiratory distress. In pneumonia, increased breathing effort may result from hypoxia or infection-related metabolic demands. Persistent tachypnea suggests worsening sepsis and requires urgent intervention.
B. Heart rate of 112 beats/minute. A heart rate ≥90 beats/minute is a SIRS criterion, often caused by infection, hypoxia, or systemic inflammation. In pneumonia, tachycardia may result from fever, pain, or compensatory mechanisms due to decreased oxygenation. An elevated heart rate in sepsis may indicate progressing hemodynamic instability.
C. Temperature of 96.1° F (35.6°C). Hypothermia (<96.8°F/36°C) is a SIRS criterion and may indicate severe sepsis or systemic inflammatory response. While fever is a common response, low temperature suggests immune system dysfunction. Hypothermia in sepsis is linked to poor prognosis and increased mortality risk.
D. White blood count of 14,000/mm³ (14 x 10⁹/L). A WBC >12,000/mm³ or <4,000/mm³ meets SIRS criteria and indicates infection-related immune activation. Elevated WBCs suggest an active inflammatory response to pneumonia. A rising WBC count may indicate worsening infection or ineffective immune control.
E. Hemoglobin of 12.8 gram/dL (7.94 mmol/L). Hemoglobin levels within the normal range (12-16 g/dL) do not indicate SIRS or sepsis progression. While anemia can develop in chronic illness or bleeding, this value does not contribute to SIRS classification. Monitoring oxygenation and perfusion is more relevant in pneumonia cases.