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An older patient has a prescription for sertraline (Zoloft) 25 mg/day, P O. to be taken for 1 week and then increased to 50 mg/day the second week. The pharmacy gives the patient 50-mg tablets. How many tablets will the patient take per day during the first week?

One and one-half tablets

One-quarter of the tablet

One tablet

Half tablet

Answer and Explanation

The Correct Answer is D

A. One and one-half tablets would exceed the prescribed dose.

B. One-quarter of a tablet would be 12.5 mg, which is less than the prescribed 25 mg.

C. One tablet would provide 50 mg, which is double the prescribed dose for the first week.

D. Half a tablet of a 50 mg tablet would correctly provide the 25 mg dose prescribed for the first week.

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Correct Answer is C

Explanation

A. Orange juice does not interact with simvastatin and does not need to be avoided.

B. Coenzyme Q10 (CoQ10) supplements are sometimes taken by patients on statins to help alleviate the side effects like muscle pain, but they do not need to be avoided.

C. Grapefruit juice should be avoided while taking simvastatin because it contains compounds that interfere with the enzymes that metabolize statins, potentially leading to increased drug levels and greater risk of side effects such as muscle damage.

D. Not all fruit juices interact with simvastatin; the specific concern is with grapefruit juice.

A. Naproxen B. Isosorbide C. Metformin D. Cefuroxime

Correct Answer is B

Explanation

A. Naproxen does not typically interact with sildenafil.

B. Sildenafil interacts with nitrates such as isosorbide, leading to severe hypotension, making it contraindicated in patients taking nitrates.

C. Metformin does not typically interact with sildenafil.

D. Cefuroxime does not typically interact with sildenafil.

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An older patient has a prescription for sertraline (Zoloft) 25 mg/day, P O. to be taken for 1 week and then increased to 50 mg/day the second week. The pharmacy gives the patient 50-mg tablets. How many tablets will the patient take per day during the first week?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is caring for a client who is taking simvastatin (Zocor). What should the nurse instruct this client to avoid while taking this medication?

Correct Answer is C

Explanation

A nurse is collecting data from a client who takes several daily medications and states that he wants to ask the provider for a prescription for sildenafil (Viagra). The nurse knows that sildenafil is contraindicated due to an interaction with which of the following client's medications?

Correct Answer is B

Explanation

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