Antimicrobics effective against only gram-positive bacteria would be termed
semisynthetic drugs.
antibiotics.
broad-spectrum drugs.
narrow-spectrum drugs.
synthetic drugs.
The Correct Answer is D
A. semisynthetic drugs: Semisynthetic drugs are chemically modified natural antibiotics designed to improve their stability, spectrum, or pharmacokinetic properties. While some may target gram-positive bacteria, the term does not specifically indicate activity against a narrow group of organisms.
B. antibiotics: Antibiotics are naturally occurring or derived substances that inhibit or kill microorganisms. This term refers broadly to the type of drug rather than the range of bacteria it affects, so it does not specifically describe drugs limited to gram-positive bacteria.
C. broad-spectrum drugs: Broad-spectrum drugs are effective against a wide range of bacteria, including both gram-positive and gram-negative organisms. They are used when the specific pathogen is unknown but are not limited to gram-positive bacteria.
D. narrow-spectrum drugs: Narrow-spectrum drugs are effective against a limited group of microorganisms. In this context, a drug that targets only gram-positive bacteria is considered narrow-spectrum, as it does not act against gram-negative organisms and allows for more targeted therapy with reduced impact on normal flora.
E. synthetic drugs: Synthetic drugs are entirely chemically synthesized rather than derived from natural sources. While some synthetic drugs may target gram-positive bacteria, the term describes the origin of the drug, not its spectrum of activity.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Allosteric site: The allosteric site is a region on the enzyme separate from the active site where regulatory molecules can bind. Binding at this site can change the enzyme’s conformation and alter its activity, either enhancing or inhibiting substrate binding, but the allosteric site does not directly interact with the substrate.
B. Active site: The active site is the specific region of the enzyme where the substrate binds. Its three-dimensional shape and chemical properties complement the substrate, allowing precise interaction. Binding at the active site facilitates the conversion of substrate to product, often stabilizing the transition state and lowering the activation energy of the reaction.
C. Induced fit site: The term “induced fit” describes the conformational change that occurs in the enzyme when the substrate binds to the active site, allowing tighter binding and optimal positioning for catalysis. It is not a separate site; rather, it refers to the dynamic adjustment of the active site itself.
D. Substrate attachment site: This is a general descriptive term and not a standard term in enzymology. The actual site where substrate molecules specifically bind is the active site, which is structurally and chemically tailored to the substrate.
Correct Answer is A
Explanation
A. Positive-sense RNA: Positive-sense RNA viruses possess genomes that function directly as messenger RNA (mRNA). After entering the host cell, the viral RNA can immediately bind to host ribosomes and begin translation to produce viral proteins. No transcription step is required before protein synthesis, these viruses can rapidly initiate replication once infection occurs.
B. Negative-sense RNA: Negative-sense RNA viruses have genomes that are complementary to mRNA and therefore cannot be translated directly by host ribosomes. Before protein synthesis can occur, the virus must first use an RNA-dependent RNA polymerase to synthesize a complementary positive-sense RNA strand. Only this newly formed RNA can function as mRNA for protein production.
C. Double-stranded RNA: Double-stranded RNA viruses contain both a positive and a negative RNA strand. However, the host cell cannot directly translate the double-stranded genome. The virus must first use viral RNA polymerase enzymes to transcribe the negative strand into a positive-sense RNA that can serve as mRNA for translation.
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