Complete the following sentence using the options in the drop down selection. _ Is what the body does with the drug versus which is what the drug does to the body.

Affinity

Efficacy

Biotransformation

Pharmacokinetics

Pharmacodynamics

Answer and Explanation

Correct Answer : D,E

A) Affinity: Affinity refers to the strength of the interaction between a drug and its receptor. It does not describe the body's overall handling of the drug or the drug's effects on the body.

B) Efficacy: Efficacy describes the ability of a drug to produce a desired therapeutic effect. It pertains to the drug’s effectiveness once it interacts with its target but does not encompass the body's handling of the drug.

C) Biotransformation: Biotransformation is the process of drug metabolism, specifically how the body chemically alters a drug. While it is a part of pharmacokinetics, it does not cover the entire concept.

D) Pharmacokinetics: Pharmacokinetics is the term used to describe what the body does with the drug, including absorption, distribution, metabolism, and excretion. It encompasses the processes that determine the drug's concentration in the body over time.

E) Pharmacodynamics: Pharmacodynamics refers to what the drug does to the body, including the relationship between drug concentration and effect. It encompasses the mechanisms of action, including receptor interactions and therapeutic effects.

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Correct Answer is B

Explanation

A) Inject a volume of less than 2 mL: While it is generally recommended to inject a volume of less than 2 mL into the deltoid muscle to avoid discomfort and ensure proper absorption, this is not the primary action to focus on when planning the injection.

B) Inject the medication at a 90 degree angle: This is the correct action. Administering an intramuscular (IM) injection at a 90-degree angle ensures that the medication is delivered deep into the muscle tissue, which is necessary for proper absorption and effectiveness.

C) Inject the medication 12.7 cm (5 in) below the client’s acromion process: The correct injection site for the deltoid muscle is typically 2-3 finger widths (approximately 2.5-5 cm) below the acromion process, not 12.7 cm. Injecting too far below the acromion process could result in an incorrect injection site.

D) Use a 21-gauge needle for the injection: While a 21-gauge needle can be used for IM injections, the gauge of the needle is not the primary focus in this context. The angle of injection is more critical to ensure proper delivery of the medication.

A. Wait for at least another 30 minutes before calling to have the level drawn. B. Schedule the level to be drawn in 8 hours C. Call the lab to have the medication level drawn immediately D. Arrange for the level to be drawn tomorrow since the peak time has passed.

Correct Answer is A

Explanation

A. Wait for at least another 30 minutes before calling to have the level drawn:
For oral medications, peak drug levels are typically drawn 1 to 2 hours after administration, depending on the medication's pharmacokinetics. Since the client took the medication only 30 minutes ago, it is premature to draw the level now. Waiting an additional 30 minutes would align with the typical peak times for oral medications, ensuring that the drug level reflects its peak concentration.

B. Schedule the level to be drawn in 8 hours:
Drawing the peak level 8 hours after administration would likely be too late, as most oral medications reach their peak concentration within 1 to 2 hours. Scheduling the level for 8 hours later may result in an inaccurate measurement of the peak drug level, leading to potentially misleading clinical information.

C. Call the lab to have the medication level drawn immediately:
Drawing the level immediately after 30 minutes may not provide an accurate representation of the peak drug level. Oral medications generally reach peak levels later, and an early draw could result in a falsely low measurement that does not reflect the drug's maximum concentration.

D. Arrange for the level to be drawn tomorrow since the peak time has passed:
The peak time has not passed, as the medication was only administered 30 minutes ago. Drawing the level tomorrow would be far too late to assess the peak concentration accurately, which is essential for evaluating the effectiveness and safety of the medication.

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Complete the following sentence using the options in the drop down selection. _____ Is what the body does with the drug versus ____ which is what the drug does to the body.

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is planning to administer an IM injection into a client's deltoid muscle. Which action should the nurse take?

Correct Answer is B

Explanation

The nurse is caring for a client who needs to have a peak drug level drawn. The client was given an oral medication 30 minutes ago. What is the best action by the nurse?

Correct Answer is A

Explanation

The healthcare provider orders azithromycin (Zithromax) 1000mg to be given as a loading dose. The nurse understands that the purpose of this loading dose is to:

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A nurse reads in a drug information guide that PO morphine has a high first-pass effect. Which of the following would the nurse expect?

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Complete the following sentence using the options in the drop down selection. _ Is what the body does with the drug versus which is what the drug does to the body.