Diabetes results from either:

Choice A reason: Cushing's is not related to this type of edema. Cushing's syndrome is a condition caused by prolonged exposure to high levels of cortisol, a hormone produced by the adrenal glands. It can lead to various symptoms, including weight gain, thinning skin, and high blood pressure, but it does not describe the specific characteristic of edema that leaves an indentation when pressed.

Choice B reason: Swelling is a general term that describes an increase in the size of a body part, often due to the accumulation of fluid. While edema is a type of swelling, the term "swelling" itself does not specifically refer to the characteristic of leaving an indentation upon pressure.

Choice C reason: Dependent edema occurs in areas of the body that are lower than the heart, often due to gravity. This type of edema can be seen in conditions like heart failure or prolonged immobility. However, it does not specifically refer to the characteristic of pitting, which is the ability to leave an indentation upon applying pressure.

Choice D reason: Pitting edema is the correct term for this condition. It occurs when pressure is applied to a swollen area, forcing fluid movement and leaving a visible indentation that persists for some time. Pitting edema is commonly seen in conditions such as congestive heart failure, liver disease, and deep vein thrombosis. The extent and duration of the indentation can help assess the severity of the edema.

Choice A reason: Type 1 diabetes is not characterized by the stimulation of glucose production due to food intake and resulting in increased insulin production. This description is more relevant to normal metabolic processes rather than the pathophysiological mechanisms underlying type 1 diabetes.

Choice B reason: The pathophysiology of type 1 diabetes is not due to decreased production of releasing hormones by the hypothalamus. While hormonal regulation plays a role in overall endocrine function, type 1 diabetes specifically involves the pancreatic islet cells.

Choice C reason: Type 1 diabetes is an autoimmune disorder where the body's immune system attacks and destroys the insulin-producing beta cells in the pancreatic islets. This destruction leads to a deficiency of insulin, which is necessary for regulating blood glucose levels. As a result, individuals with type 1 diabetes must rely on exogenous insulin to manage their blood sugar levels.

Choice D reason: Insulin resistance, where insulin-sensitive tissues do not respond effectively to insulin, is a characteristic of type 2 diabetes, not type 1 diabetes. In type 1 diabetes, the issue is the lack of insulin production due to the destruction of the pancreatic islet cells.