Every state in the U.S. requires that newborns be tested for which of the following disorders?
Septicemia
Bacteremia
Phenylketonuria
Proteinuria
The Correct Answer is C
Choice A reason:
Septicemia, also known as sepsis, is a serious bloodstream infection that can be life-threatening. It is not a disorder that is screened for at birth because it is not a congenital condition but rather an infection that can occur at any time when bacteria enter the bloodstream.
Choice B reason:
Bacteremia refers to the presence of bacteria in the bloodstream and, like septicemia, is not a congenital disorder. It is not typically screened for at birth as it is an acquired condition that can occur after exposure to bacteria.
Choice C reason:
Phenylketonuria (PKU) is a genetic disorder that results in an inability to metabolize the amino acid phenylalanine. Untreated, PKU can lead to intellectual disability, seizures, and other serious health problems. Newborn screening for PKU is required in every state in the U.S. because early detection and dietary treatment can prevent the severe consequences of the disorder.
Choice D reason:
Proteinuria is the presence of abnormal amounts of protein in the urine, which can be a sign of kidney disease. It is not a condition that is screened for at birth as part of the standard newborn screening panel.
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Related Questions
Correct Answer is C
Explanation
Choice A reason:
Holding the two slides at a 90-degree angle is not the correct technique for performing a blood smear. This angle is too steep and would not allow the blood to spread thinly across the slide, which is necessary for creating a quality smear that can be examined under a microscope.
Choice B reason:
Allowing the blood drop to clot slightly before performing the smear is not advisable. Clotting can interfere with the spread of the blood and the formation of a monolayer, which is essential for accurate microscopic examination. The blood should be fresh and anticoagulated to prevent clotting.
Choice C reason:
Holding the slides at a 30-degree angle is the correct technique for performing a blood smear. This angle allows the spreader slide to push the blood drop smoothly across the patient slide, creating a thin, even layer of blood that is ideal for microscopic analysis. The angle, speed, and pressure must be consistent to achieve a quality smear.
Choice D reason:
Allowing the blood drop to clot completely before performing the smear would make it impossible to create a smear. Clotted blood cannot be spread into a thin layer, which is necessary for microscopic examination of the blood cells.
Correct Answer is A
Explanation
Choice A reason:
Glucose and triglyceride levels are influenced by recent food intake, so it is essential to measure these levels after a period of fasting to obtain accurate results. Fasting ensures that the glucose measurement reflects the body's baseline glucose level without the influence of a recent meal, which is crucial for diagnosing and managing conditions like diabetes. Similarly, triglycerides, which are fats in the blood, can be elevated after eating, so a fasting sample gives a clear picture of the lipid profile for assessing cardiovascular risk.
Choice B reason:
While BUN (Blood Urea Nitrogen) levels can be affected by diet, fasting is not typically required for BUN or alkaline phosphatase tests. These tests are often part of a comprehensive metabolic panel that may or may not require fasting. However, fasting is not specifically necessary for accurate measurement of these two tests.
Choice C reason:
Creatinine and total protein levels are generally not affected by short-term dietary intake, so fasting is not required for these tests. Creatinine is a waste product from muscle metabolism and is used to evaluate kidney function, while total protein levels can indicate a variety of conditions including liver and kidney disorders, but they reflect the body's long-term nutritional status rather than immediate food intake.
Choice D reason:
Lactate dehydrogenase (LDH) and albumin tests do not require fasting. LDH is an enzyme found in almost all body tissues and is released into the bloodstream when tissues are damaged, so its levels are not dependent on food intake. Albumin is the most abundant protein in the blood and is produced by the liver; its levels are used to assess liver and kidney function, nutritional status, and other conditions, but fasting is not necessary for accurate measurement.
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