In the kidney, where are the mechanisms found that are responsible for increasing urine concentration?
Calyx.
Proximal convoluted tubule.
Renal pelvis.
The loop of Henle.
The Correct Answer is D
The loop of Henle, a critical structure within the nephron of the kidney, plays a key role in the concentration of urine through the process of countercurrent multiplication. Here's why option D is the correct choice:
A) Calyx:
The calyx is a structure in the kidney that collects urine from the renal papillae and channels it into the renal pelvis. It does not directly participate in the concentration of urine.
B) Proximal convoluted tubule:
The proximal convoluted tubule primarily reabsorbs water, electrolytes, and nutrients from the glomerular filtrate, but it does not contribute significantly to the concentration of urine.
C) Renal pelvis:
The renal pelvis is a funnel-shaped structure that collects urine from the calyces and funnels it into the ureter. It is not directly involved in the concentration of urine.
D) The loop of Henle:
Correct. The loop of Henle is the nephron segment responsible for generating a hypertonic medullary interstitium, which creates the osmotic gradient necessary for urine concentration. The loop of Henle achieves this through countercurrent multiplication, where the descending limb allows passive reabsorption of water, while the ascending limb actively pumps out sodium and chloride ions. This creates an osmotic gradient that allows for further water reabsorption in the collecting ducts, leading to concentrated urine.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
The ABG results indicate respiratory acidosis (pH 7.0, PaCO2 66 mmHg) with compensatory metabolic alkalosis (HCO3- 24 mEq/L). The low PaO2 (60 mmHg) suggests hypoxemia.
pH 7.0: The pH is below the normal range (7.35 to 7.45), indicating acidosis.
PaCO2 66 mmHg: The PaCO2 is elevated above the normal range (35 to 45 mmHg), indicating respiratory acidosis.
HCO3- 24 mEq/L: The bicarbonate level is within the normal range (21 to 28 mEq/L), indicating compensatory metabolic alkalosis.
PaO2 60 mmHg: The PaO2 is decreased below the normal range (80 to 100 mmHg), indicating hypoxemia.
These findings suggest that the client is experiencing respiratory failure, which is characterized by inadequate gas exchange resulting in hypoxemia and hypercapnia. In this case, the massive pulmonary embolus is causing ventilation-perfusion (V/Q) mismatch, leading to impaired gas exchange and respiratory compromise. Tachycardia, hypotension, and audible bilateral pulmonary crackles further support the diagnosis of respiratory failure in the context of a massive pulmonary embolus.
Correct Answer is C
Explanation
Smoking is a well-established risk factor for lung cancer, and the pathophysiological process underlying this association involves the exposure of the lungs to carcinogenic agents present in tobacco smoke. Here's why option C is the correct choice:
A) Vasoconstrictive properties of nicotine reduce oxygenation and stimulate metabolism:
While nicotine is a primary addictive component of tobacco smoke and can lead to vasoconstriction, reduced oxygenation, and increased metabolism, these effects primarily contribute to cardiovascular diseases associated with smoking, such as coronary artery disease and stroke, rather than the development of lung cancer.
B) Drug addiction changes the neurochemical messages in the brain causing cravings:
This statement addresses the addictive nature of nicotine and its impact on neurochemistry, leading to cravings and dependence. While addiction is a significant aspect of tobacco use, it does not directly explain the pathophysiological process by which smoking causes lung cancer.
C) Carcinogenic agents in tobacco alter cellular cytology, morphology, and function of the lung:
Correct. Tobacco smoke contains numerous carcinogenic compounds, such as polycyclic aromatic hydrocarbons (PAHs), nitrosamines, and benzene, which can directly damage the DNA of lung cells. This DNA damage can lead to mutations and alterations in cellular cytology, morphology, and function, ultimately contributing to the development of lung cancer.
D) Risk for comorbidities increase incidence of chronic diseases and decrease longevity:
While smoking is associated with an increased risk of various comorbidities and chronic diseases, such as cardiovascular diseases, respiratory diseases, and certain cancers, this option does not specifically address the pathophysiological process of lung cancer development.
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