Mrs. Kalen is a 70 year old female who has arrived into the ER due to persistent vomiting for two days now. She appears to be lethargic and weak and has myalgia. She is noted to have dry mucus membranes and her capillary refill takes >4 seconds. She is diagnosed as having gastroenteritis and dehydration. Measurement of arterial blood gas shows pH 7.5, PaO2 85 mm Hg, PaCO2 40 mm Hg, and HCO3 34 mmol/L. What would you interpret the acid-base disorder to be?
Uncompensated Respiratory Acidosis
Fully Compensated Metabolic Acidosis
Uncompensated Metabolic Alkalosis
Partially Compensated Respiratory Alkalosis
The Correct Answer is C
The pH value of 7.5 indicates alkalosis, as it is above the normal range of 7.35-7.45. The elevated bicarbonate (HCO3-) level of 34 mmol/L suggests metabolic alkalosis, as it is higher than the normal range of 22-28 mmol/L. The PaCO2 level of 40 mm Hg falls within the normal range of 35-45 mm Hg.
In this case, the primary disturbance is metabolic alkalosis, which is likely caused by vomiting leading to excessive loss of gastric acid (hydrogen ions) and chloride ions from the stomach. This loss of acid and chloride results in an imbalance of electrolytes and an increase in bicarbonate levels, leading to metabolic alkalosis.
The arterial blood gas results do not indicate any compensation. Compensation occurs when the body attempts to restore the pH balance by adjusting the respiratory or metabolic systems. In this case, there is no compensation observed because the PaCO2 level is within the normal range and not significantly altered.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Cephalosporins are similar to another group of beta-lactam antibiotics called the Penicillins. Both cephalosporins and penicillins belong to the beta-lactam class of antibiotics, which share a similar structure and mechanism of action. They inhibit bacterial cell wall synthesis by binding to specific proteins called penicillin-binding proteins (PBPs), leading to bacterial cell death. This shared mechanism of action makes cephalosporins and penicillins similar in their antibacterial effects.
On the other hand, macrolides, fluoroquinolones, and aminoglycosides are different classes of antibiotics with distinct structures and mechanisms of action. They work through different mechanisms to inhibit bacterial growth and have different spectrums of activity compared to beta-lactam antibiotics like cephalosporins and penicillins.
Correct Answer is C
Explanation
Excessive exposure to UV light, such as sunlight or tanning beds, is a known trigger for SLE exacerbations. It is important for individuals with SLE to protect their skin from the sun by wearing protective clothing, using sunscreen, and avoiding direct sunlight during peak hours. Having a family history of SLE increases the risk of developing the disease. While it is not a trigger in itself, it is an important piece of information for the client to be aware of, as it may indicate a genetic predisposition to the condition.
Acetaminophen is a commonly used over-the-counter pain reliever. While it can help manage pain associated with SLE, it is not typically considered a trigger for exacerbations. Menopause, which marks the end of a woman's reproductive years, does not directly trigger SLE exacerbations. However, hormonal changes during menopause can potentially affect disease activity in some individuals. It is important for the client to discuss any changes or concerns with their healthcare provider to manage their symptoms effectively.
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