A client who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection. While taking the client’s history, the nurse determines that the client has been self-administering St. John’s Wort, an herbal preparation, on the advice of a friend. Which information is most significant about this finding?

Choice A: Place the client on a cardiorespiratory monitor

Reason: Placing the client on a cardiorespiratory monitor is crucial in this scenario because the client is experiencing heart palpitations, dizziness, and lightheadedness, which are indicative of a potential tachydysrhythmia. A cardiorespiratory monitor will continuously track the heart rate and rhythm, allowing for immediate detection of any abnormal heart rhythms. This is essential for timely intervention and management of any life-threatening arrhythmias. Continuous monitoring also helps in assessing the effectiveness of any treatments administered and in making necessary adjustments.

Choice B: Administer diphenhydramine

Reason: Diphenhydramine is an antihistamine commonly used to treat allergic reactions and symptoms of anaphylaxis. However, in this case, the client does not exhibit symptoms of an allergic reaction or anaphylaxis, such as hives, swelling, or difficulty breathing. The primary concern here is the heart palpitations and dizziness, which are more indicative of a cardiac issue rather than an allergic reaction. Therefore, administering diphenhydramine would not address the underlying problem and is not the appropriate action in this scenario.

Choice C: Give a dose of albuterol

Reason: Albuterol is a bronchodilator used to relieve bronchospasm in conditions like asthma. Although the client has moderate persistent asthma and has been using albuterol, the current symptoms of heart palpitations and dizziness suggest a possible overuse of albuterol, leading to tachydysrhythmia. However, in the context of an acute asthma exacerbation, administering albuterol can still be necessary to manage bronchospasm. It is important to balance the need for bronchodilation with the risk of exacerbating tachydysrhythmia. Therefore, giving a dose of albuterol should be carefully considered and monitored.

Choice D: Anaphylaxis

Reason: Anaphylaxis is a severe, life-threatening allergic reaction that requires immediate treatment with epinephrine. The client does not present with symptoms typical of anaphylaxis, such as hives, swelling, or difficulty breathing. Instead, the symptoms of heart palpitations, dizziness, and lightheadedness are more consistent with a cardiac issue. Additionally, the client’s oxygen saturation is 99% on room air, which is not indicative of anaphylaxis. Therefore, anaphylaxis is not the most likely condition in this scenario.

Choice E: Tachydysrhythmia

Reason: Tachydysrhythmia refers to an abnormal heart rhythm with a rapid rate, which can cause symptoms such as heart palpitations, dizziness, and lightheadedness. The client’s symptoms, along with the history of using multiple doses of albuterol, suggest that she may be experiencing a tachydysrhythmia. Albuterol, a beta-agonist, can cause tachycardia and palpitations, especially when used frequently. Therefore, tachydysrhythmia is the most likely condition the client is experiencing.

Choice F: Anemia

Reason: Anemia is a condition characterized by a deficiency of red blood cells or hemoglobin, leading to symptoms such as fatigue, weakness, and dizziness. While dizziness and lightheadedness can be symptoms of anemia, the client’s presentation of heart palpitations and the context of asthma management with frequent albuterol use point more towards a cardiac issue rather than anemia. Additionally, there is no mention of other common symptoms of anemia, such as pallor or fatigue, in the client’s history and physical examination.

Choice G: Breath sounds

Reason: Monitoring breath sounds is essential in assessing the respiratory status of a client with asthma. Changes in breath sounds can indicate the presence of bronchospasm, airway obstruction, or other respiratory complications. In this scenario, monitoring breath sounds will help assess the effectiveness of albuterol treatment and detect any worsening of asthma symptoms. It is also important to ensure that the client’s respiratory status remains stable while addressing the cardiac issue.

Choice H: Airway edema

Reason: Monitoring for airway edema is important in clients with asthma, as it can indicate inflammation and swelling of the airways, leading to obstruction and difficulty breathing. In this case, while the primary concern is the cardiac symptoms, it is still important to monitor for any signs of airway edema, especially given the client’s history of asthma and recent exacerbation of symptoms. This will help in managing the respiratory aspect of the client’s condition and ensuring comprehensive care.

Choice I: Iron level

Reason: Monitoring iron levels is relevant in the context of anemia, as low iron levels can indicate iron deficiency anemia. However, in this scenario, the client’s symptoms and history do not suggest anemia as the primary issue. The focus should be on monitoring parameters related to the cardiac and respiratory systems, given the client’s presentation of heart palpitations, dizziness, and asthma exacerbation. Therefore, monitoring iron levels is not a priority in this case.

Captopril is an angiotensin converting enzyme inhibitor that works by vasodilation.

Choice A: Angiotensin Converting Enzyme Inhibitor

Reason:

Captopril is classified as an angiotensin converting enzyme (ACE) inhibitor. ACE inhibitors work by blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. By inhibiting this conversion, ACE inhibitors reduce the levels of angiotensin II, leading to vasodilation, decreased blood pressure, and reduced workload on the heart. This mechanism is particularly beneficial in managing hypertension and heart failure. Additionally, ACE inhibitors like captopril help in reducing the progression of diabetic nephropathy by decreasing glomerular pressure.

Choice B: Aldosterone Agonist

Reason:

Aldosterone agonists are drugs that mimic the action of aldosterone, a hormone that increases sodium and water reabsorption in the kidneys, leading to increased blood volume and blood pressure. This is the opposite of what captopril does. Captopril, as an ACE inhibitor, actually reduces aldosterone secretion, leading to decreased sodium and water retention, which helps lower blood pressure. Therefore, captopril cannot be classified as an aldosterone agonist.

Choice C: Angiotensin II Receptor Blocker

Reason:

Angiotensin II receptor blockers (ARBs) work by blocking the action of angiotensin II at its receptor sites, preventing vasoconstriction and aldosterone secretion. While ARBs and ACE inhibitors both target the renin-angiotensin-aldosterone system (RAAS), they do so at different points. Captopril is an ACE inhibitor, not an ARB. ARBs include drugs like losartan and valsartan, which are used when patients cannot tolerate ACE inhibitors due to side effects like coug.

Choice D: Lowering the Heart Rate

Reason:

Lowering the heart rate is not the primary mechanism of action for captopril. This effect is more commonly associated with beta-blockers, which reduce heart rate and myocardial contractility to lower blood pressure and reduce cardiac workload. Captopril, on the other hand, primarily works through vasodilation by inhibiting the formation of angiotensin II. While it may have some indirect effects on heart rate by reducing blood pressure, this is not its main mechanism.

Choice E: Reducing Inflammation

Reason:

Reducing inflammation is not a primary action of captopril. Anti-inflammatory effects are typically associated with nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids. While there is some evidence that ACE inhibitors may have minor anti-inflammatory effects due to their impact on the RAAS, this is not their primary function. Captopril is mainly used for its vasodilatory effects to manage hypertension and heart failure.

Choice F: Diuresis

Reason:

Diuresis, or increased urine production, is not the primary mechanism of action for captopril. Diuretics, such as furosemide or hydrochlorothiazide, are specifically used to promote diuresis by acting on different parts of the renal tubules to increase the excretion of sodium and water. While captopril can lead to mild diuresis by reducing aldosterone levels, this is not its main therapeutic action.

Choice G: Vasodilation

Reason:

Vasodilation is the correct mechanism of action for captopril. By inhibiting the conversion of angiotensin I to angiotensin II, captopril reduces vasoconstriction and promotes vasodilation. This leads to a decrease in blood pressure and an overall reduction in the workload on the heart. Vasodilation is a key therapeutic effect of ACE inhibitors, making them effective in treating conditions like hypertension and heart failure.