Order: Levaquin 350 mg is added to 500 mL D5W to infuse over 8 hours. Drop factor: 10 gtt/mL. For IV reconstitute with 1o mL. of diluent to get 100 mg per 10 mL. (Consider the medication added in the volume of fluid.) Calculate the rate in gtt/min at which the IV should infuse

Given:

Ordered dose of Augmentin: 250 mg

Drug comes in a 2 gram vial

Reconstituted volume: 77.2 mL

Concentration after reconstitution: 125 mg/5 mL

Step 1: Calculate the total volume of the reconstituted solution:

Total volume = 77.2 mL

Step 2: Calculate the total amount of Augmentin in the solution:

Total amount (mg) = Concentration (mg/mL) x Total volume (mL)

Total amount (mg) = 125 mg/5 mL x 77.2 mL

Total amount (mg) = 1930 mg

Step 3: Determine the number of doses in the vial:

Number of doses = Total amount (mg) / Ordered dose (mg/dose)

Number of doses = 1930 mg / 250 mg/dose

Number of doses = 7.72 doses

Step 4: Calculate the volume per dose:

Volume per dose (mL) = Total volume (mL) / Number of doses

Volume per dose (mL) = 77.2 mL / 7.72 doses

Volume per dose (mL) = 10 mL

A) They should not be abruptly stopped:
Beta blockers should not be abruptly discontinued because sudden withdrawal can lead to rebound hypertension, tachycardia, and even a risk of acute myocardial infarction (MI) in patients with heart disease. Gradual tapering is recommended to allow the body to adjust and avoid these adverse effects.

B) They are safe to take with herbal medications:
Herbal medications can interact with beta blockers and alter their effectiveness or increase the risk of side effects. For example, herbs like St. John's wort can decrease the effectiveness of beta blockers, while others like ginseng may increase the risk of side effects like high blood pressure. It is important to consult with a healthcare provider before taking any herbal supplements with beta blockers.

C) It isn't necessary to monitor lab results:
While beta blockers don't require regular lab tests for their direct effects, monitoring is important in certain patients, especially those with underlying conditions like heart failure, kidney disease, or diabetes. For example, monitoring renal function, electrolytes, and blood glucose may be necessary for patients who are taking other medications alongside beta blockers or who have coexisting conditions.

D) Taking over-the-counter medications is acceptable:
Many over-the-counter (OTC) medications can interact with beta blockers and affect their effectiveness or cause adverse effects. For example, decongestants (found in many cold medications) can raise blood pressure and counteract the effects of beta blockers.