Phenytoin has a narrow therapeutic index. The nurse recognizes that this characteristic indicates which of these?

The phenytoin has a low chance of being effective.

There is no difference between safe and toxic plasma levels.

Avery small dosage can result in the desired therapeutic effect.

The safe and the toxic plasma levels of the drug are very close to each other.

Answer and Explanation

The Correct Answer is D

D. Therapeutic index refers to the doses that results in desired outcome with adverse effects. It is between the safe and toxic levels. Narrow therapeutic level means the two are very close.
A. How effective a drug is termed as efficacy
B. Such a drug does not exist as it is not safe
C. Effectiveness of very small dose is termed as potency

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Correct Answer is ["A","B","D"]

Explanation

The sympathetic nervous system leads to increased heart rate, vasoconstriction with increasing blood pressure and decreased salivary glands secretion.

C and E- parasympathetic activity

A. Restricting fluids while the client is on this medication B. Administer the drug over at least 60 minutes C. Reporting a trough drug level of24 mcg/mL and holding the drug D. Monitoring serum creatinine levels E. Instructing the client to report dizziness or a feeling of fullness in the ears

Correct Answer is ["B","C","D","E"]

Explanation

A. vancomycin can be nephrotoxic and fluid restriction is inappropriate
B. Slow infusion of vancomycin is key to avoid flush reactions
C. Normal trough levels for vancomycin are 10-20mcg/ml- 24mcg/ml increases risk of toxicity
D. Monitoring serum creatinine monitors for renal damage
E. Vancomycin can cause hearing loss and clients should be advised any early signs of ototoxicitysuch as ear fullness

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Phenytoin has a narrow therapeutic index. The nurse recognizes that this characteristic indicates which of these?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is caring for a client experiencing sympathetic nervous system stimulation. What assessment finding supports this diagnosis? Select all that apply.

Correct Answer is ["A","B","D"]

Explanation

The nurse is administering intravenous vancomycin to a client who has had gastrointestinal surgery. Which nursing measures are appropriate? (Select all that apply.)

Correct Answer is ["B","C","D","E"]

Explanation

A client is receiving gabapentin, an anticonvulsant, but has no history of seizures. The nurse expects that the client is receiving this drug for which condition?

The nurse is administering intravenous vancomycin to a client who has had gastrointestinal surgery. Which nursing measures are appropriate? (Select all that apply.)

A client who has been taking cimetidine for hyperacidity calls the clinic to say that the medication has not been effective. The nurse reviews his history and notes that which factor may be influencing the effectiveness of this drug?

A nurse is administering nasal decongestant drops for a client. Which of the following actions should the nurse take?

The nurse is developing a care plan for a client who will be self-administering a metered-dose inhaler. Which statement reflects a measurable outcome?

Methotrexate is ordered for a client with a malignant tumor, and the nurse is providing education about self-care after the chemotherapy is given. Which statements by the nurse are appropriate for the client receiving methotrexate? (Select all that apply.)

A client who has a history of myocardial infarction (Ml) is prescribed aspirin 325 mg. The nurse recognizes that the aspirin is given due to which of the following actions of the medications?