Phenytoin has a narrow therapeutic index. The nurse recognizes that this characteristic indicates which of these?

The phenytoin has a low chance of being effective.

There is no difference between safe and toxic plasma levels.

Avery small dosage can result in the desired therapeutic effect.

The safe and the toxic plasma levels of the drug are very close to each other.

Answer and Explanation

The Correct Answer is D

D. Therapeutic index refers to the doses that results in desired outcome with adverse effects. It is between the safe and toxic levels. Narrow therapeutic level means the two are very close.
A. How effective a drug is termed as efficacy
B. Such a drug does not exist as it is not safe
C. Effectiveness of very small dose is termed as potency

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Correct Answer is A

Explanation

A. alcohol interacts with phenytoin leading to CNS depression
B. Antacids reduces the oral absorption of phenytoin
C. Phenytoin causes gingival hyperplasia and the client should maintain good oral hygiene to prevent secondary infection
D. Phenytoin can turn urine red but not blue.

A. Hair loss is not expected with this drug. B. Avoid foods that are too hot or too cold or rough in texture. C. Avoid areas with large crowds or gatherings. D. Prepare for hair loss. E. Restrict fluid intake to reduce nausea and vomiting.

Correct Answer is ["B","C","D"]

Explanation

methotrexate interferes with DNA synthesis which may affect all rapidly dividing cells including hair follicles, oral epithelial lining and bone marrow cells involved in fighting against infections
A. Hair loss is expected
B, E. Methotrexate should be taken with a lot of fluid to flush down the drug to minimize nausea and vomiting

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Phenytoin has a narrow therapeutic index. The nurse recognizes that this characteristic indicates which of these?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is providing teaching to a client who has seizures and a new prescription for phenytoin. Which of the following information should the nurse provide?

Correct Answer is A

Explanation

Methotrexate is ordered for a client with a malignant tumor, and the nurse is providing education about self-care after the chemotherapy is given. Which statements by the nurse are appropriate for the client receiving methotrexate? (Select all that apply.)

Correct Answer is ["B","C","D"]

Explanation

The nurse is screening a client who will be taking a nonspecific/nonselective beta blocker. Which condition, if present, may cause serious problems if the client takes this medication?

A nurse is providing teaching a client who has rheumatoid arthritis and a new prescription for methotrexate. Which of the following instructions should the nurse include? (Select all that apply.)

When taking a telephone order for a medication, which action by the nurse is most appropriate?

A client who has received some traumatic news is panicking and asks for some medication to help settle down. The nurse anticipates giving which drug that is most appropriate for this situation?

The nurse is evaluating the laboratory results of a client who has received chemotherapy. The loss of which blood cell leads to lack of energy, fatigue, intolerance of activity and hypoxemia?

A client who has received chemotherapy has a critically low platelet count. The nurse expects which drug or drug class to be used to stimulate platelet cell production?

A client with a tracheostomy has difficulty removing excessive, thick mucus from the respiratory tract. The nurse expects that which drug will be ordered to aid in the removal of mucus?