The client with gout is prescribed allopurinol. Dosing will be adjusted based on
Target serum drug levels
Absence of Gl effects
Serum creatinine
Plasma urate level
The Correct Answer is D
Choice A rationale: Allopurinol dosing is not typically adjusted based on target serum drug levels.
Choice B rationale: The absence of gastrointestinal (GI) effects is not a parameter used to adjust the dosing of allopurinol.
Choice C rationale: This is partially correct. Allopurinol dosing is adjusted based on renal function, but specifically, it is adjusted based on serum creatinine levels. The higher the creatinine levels, the lower the dose of allopurinol should be.
Choice D rationale: This is correct. Allopurinol dosing is adjusted based on plasma urate levels. The goal is to reduce uric acid levels in the blood to prevent the formation of urate crystals and subsequent gout attacks. Regular monitoring of plasma urate levels helps determine the effectiveness of the medication, and adjustments can be made to achieve the target urate level.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale: While a decreased frequency of migraine headaches is a positive outcome, it does not directly indicate the immediate therapeutic effect of a sumatriptan (a serotonin receptor agonist). It may suggest a preventive effect over time.
Choice B rationale: Complete absence of migraine headaches is a positive outcome, but it is not always achievable. Immediate cessation of all headaches might not be realistic with every dose.
Choice C rationale: This is correct. Sumatriptan, a serotonin receptor agonist, is designed to terminate or relieve an ongoing migraine headache when administered during an attack. The patient reporting the termination of the migraine headache after drug administration suggests the desired therapeutic effect.
Choice D rationale: Increased nausea is not a desired therapeutic effect of sumatriptan. Sumatriptan is used to relieve the symptoms of migraines, including nausea, not exacerbate them.
Correct Answer is D
Explanation
Choice A rationale: Taking pramipexole with food can help reduce the risk of nausea, making this statement accurate.
Choice B rationale: Hallucinations are a potential side effect of dopamine agonists, so this statement is correct.
Choice C rationale: Rising slowly can help minimize orthostatic hypotension, a common side effect of dopamine agonists, making this statement accurate.
Choice D rationale: Pramipexole and other dopamine agonists help manage symptoms but do not stop the progression of Parkinson's disease. Further education is needed on the realistic expectations of the medication.
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