The client with gout is prescribed allopurinol. Dosing will be adjusted based on
Target serum drug levels
Absence of Gl effects
Serum creatinine
Plasma urate level
The Correct Answer is D
Choice A rationale: Allopurinol dosing is not typically adjusted based on target serum drug levels.
Choice B rationale: The absence of gastrointestinal (GI) effects is not a parameter used to adjust the dosing of allopurinol.
Choice C rationale: This is partially correct. Allopurinol dosing is adjusted based on renal function, but specifically, it is adjusted based on serum creatinine levels. The higher the creatinine levels, the lower the dose of allopurinol should be.
Choice D rationale: This is correct. Allopurinol dosing is adjusted based on plasma urate levels. The goal is to reduce uric acid levels in the blood to prevent the formation of urate crystals and subsequent gout attacks. Regular monitoring of plasma urate levels helps determine the effectiveness of the medication, and adjustments can be made to achieve the target urate level.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale: Norepinephrine is a neurotransmitter that is active in both the peripheral and central nervous systems.
Choice B rationale: Serotonin is primarily active in the central nervous system.
Choice C rationale: Substance P is a neurotransmitter that functions more in the peripheral nervous system.
Choice D rationale: Dynorphins primarily function in the central nervous system.
Correct Answer is B
Explanation
Choice A rationale: Epinephrine does increase the speed of conduction, but it does not significantly contribute to gluconeogenesis.
Choice B rationale: Epinephrine is used in cardiac arrest to increase heart rate, contractility, and conduction. In asthma, it causes bronchodilation.
Choice C rationale: While epinephrine can cause some vasodilation, it is not a primary indication for its use in cardiac arrest or status asthmaticus.
Choice D rationale: Epinephrine causes bronchodilation, not bronchoconstriction.
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