The client with gout is prescribed allopurinol. Dosing will be adjusted based on
Target serum drug levels
Absence of Gl effects
Serum creatinine
Plasma urate level
The Correct Answer is D
Choice A rationale: Allopurinol dosing is not typically adjusted based on target serum drug levels.
Choice B rationale: The absence of gastrointestinal (GI) effects is not a parameter used to adjust the dosing of allopurinol.
Choice C rationale: This is partially correct. Allopurinol dosing is adjusted based on renal function, but specifically, it is adjusted based on serum creatinine levels. The higher the creatinine levels, the lower the dose of allopurinol should be.
Choice D rationale: This is correct. Allopurinol dosing is adjusted based on plasma urate levels. The goal is to reduce uric acid levels in the blood to prevent the formation of urate crystals and subsequent gout attacks. Regular monitoring of plasma urate levels helps determine the effectiveness of the medication, and adjustments can be made to achieve the target urate level.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale: Loss of consciousness is a serious adverse reaction that should be reported to the healthcare provider. Instructing the wife to call the provider if it happens again is an appropriate response.
Choice B rationale: Stopping the medication without consulting the provider may not be advisable, as sudden discontinuation of some medications can have adverse effects.
Choice C rationale: Taking the next dose with food may be a general recommendation for some medications, but it does not directly address the issue of loss of consciousness.
Choice D rationale: While moving slowly when changing positions is a general recommendation for some medications, the immediate concern is the loss of consciousness, and contacting the provider is more appropriate.
Correct Answer is A
Explanation
Choice A rationale: Alprazolam (Xanax) exerts its therapeutic effect by interacting with gamma-aminobutyric acid (GABA) receptors, leading to anxiolytic and sedative effects.
Choice B rationale: Norepinephrine is not the primary neurotransmitter affected by alprazolam.
Choice C rationale: Acetylcholine is not the primary neurotransmitter affected by alprazolam.
Choice D rationale: Serotonin (5-HT) is not the primary neurotransmitter affected by alprazolam.
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