The nurse is asked by a client to explain the differences and similarities between methadone and buprenorphine for treatment of opioid use disorder. The nurse's best response is

Choice A rationale: While a decreased frequency of migraine headaches is a positive outcome, it does not directly indicate the immediate therapeutic effect of a sumatriptan (a serotonin receptor agonist). It may suggest a preventive effect over time.
Choice B rationale: Complete absence of migraine headaches is a positive outcome, but it is not always achievable. Immediate cessation of all headaches might not be realistic with every dose.
Choice C rationale: This is correct. Sumatriptan, a serotonin receptor agonist, is designed to terminate or relieve an ongoing migraine headache when administered during an attack. The patient reporting the termination of the migraine headache after drug administration suggests the desired therapeutic effect.
Choice D rationale: Increased nausea is not a desired therapeutic effect of sumatriptan. Sumatriptan is used to relieve the symptoms of migraines, including nausea, not exacerbate them.

Choice A rationale: Stopping aspirin immediately may not be necessary and can increase the risk of rebound thrombosis. A gradual discontinuation is often recommended.
Choice B rationale: Stopping aspirin 3 days prior to surgery is a common recommendation to minimize the risk of bleeding during and after the surgical procedure.
Choice C rationale: Reducing the aspirin dosage may not be sufficient, and complete discontinuation is often advised before surgery.
Choice D rationale: Continuing aspirin as scheduled can increase the risk of bleeding during and after surgery. It is generally recommended to discontinue aspirin before elective surgical procedures.