The doctor orders Augmentin 250 mg po q6h. The drug comes in a 2 gram vial. Directions say to reconstitute with 77.2 mL of sterile water to yield a solution of 125 mg/5 mL. How many mL will you administer to the client for the correct dose?
2 mL
8 mL
10mL
15 mL
The Correct Answer is C
Given:
Ordered dose of Augmentin: 250 mg
Drug comes in a 2 gram vial
Reconstituted volume: 77.2 mL
Concentration after reconstitution: 125 mg/5 mL
Step 1: Calculate the total volume of the reconstituted solution:
Total volume = 77.2 mL
Step 2: Calculate the total amount of Augmentin in the solution:
Total amount (mg) = Concentration (mg/mL) x Total volume (mL)
Total amount (mg) = 125 mg/5 mL x 77.2 mL
Total amount (mg) = 1930 mg
Step 3: Determine the number of doses in the vial:
Number of doses = Total amount (mg) / Ordered dose (mg/dose)
Number of doses = 1930 mg / 250 mg/dose
Number of doses = 7.72 doses
Step 4: Calculate the volume per dose:
Volume per dose (mL) = Total volume (mL) / Number of doses
Volume per dose (mL) = 77.2 mL / 7.72 doses
Volume per dose (mL) = 10 mL
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A) Headache:
Headache is a known side effect of angiotensin receptor blockers (ARBs), such as losartan, valsartan, and olmesartan. These medications can cause headaches due to their vasodilatory effects, which can lead to changes in blood pressure and blood flow. While not everyone will experience this side effect, it is considered relatively common.
B) Dizziness:
Dizziness is another common side effect of ARBs. As ARBs cause vasodilation by blocking the angiotensin II receptors, they can lower blood pressure, leading to dizziness or lightheadedness, especially when standing up quickly. This is particularly noticeable in patients who are elderly or who are on multiple antihypertensive medications.
C) Constipation:
Constipation is not a typical side effect of angiotensin receptor blockers (ARBs). While some medications, especially calcium channel blockers and certain opioid analgesics, are more commonly associated with constipation, ARBs do not have this effect. ARBs primarily affect the vascular system and the kidneys, and constipation is not generally a side effect.
D) Hypotension:
Hypotension (low blood pressure) is a common side effect of ARBs. Since these medications relax blood vessels and decrease blood pressure by blocking the effects of angiotensin II, they can lead to a drop in blood pressure, particularly in the first few days of treatment or when starting therapy. This can result in symptoms like dizziness or fainting, especially when changing positions (postural hypotension).
Correct Answer is B
Explanation
The concentration provided is 0.5 g/3 mL.
Convert grams to milligrams:
0.5g=500mg
Now, the concentration is 500 mg/3 mL.
Find the concentration in mg/mL:
Concentration=(500mg/3mL)≈166.67mg/mL
Next, to find the volume needed for a 10 mg dose, use the formula:
Volume=(Desireddose(mg)/Concentration(mg/mL)
10mg/166.67mg/mL≈0.06mL/dose
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