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The healthcare provider prescribes ganciclovir 375 mg intravenous (IV) every 12 hour to infuse over 90 minutes. The pharmacy delivers ganciclovir 375 mg in a 150 mL IV bag. How many drops/minute should the nurse regulate the gravity infusion using a drip chamber that delivers 10 drops/mL? (Enter numerical value only. If rounding is required, round to the nearest whole number.)

Answer and Explanation

The Correct Answer is ["17"]

Here's how to calculate the drip rate (drops/minute) for the ganciclovir infusion:

1. We know:

Ganciclovir dose: 375 mg (given)

Infusion bag volume: 150 mL (given)

Infusion time: 90 minutes (given) = 1.5 hours (convert minutes to hours)

Drip chamber calibration: 10 drops/mL (given)

2. We need to find:

Drip rate (drops/minute)

3. Steps:

Calculate the concentration of ganciclovir in the bag (assuming all medication is in the bag):

Concentration (mg/mL) = Dose (mg) / Volume (mL)

Concentration (mg/mL) = 375 mg / 150 mL

Concentration (mg/mL) = 2.5 mg/mL

Calculate the total volume to infuse (considering the prescribed dose):

We already know the volume of the bag (150 mL), but this might contain more volume than needed to deliver the prescribed dose.

Calculate the volume to infuse based on the dose and concentration:

Volume to infuse (mL) = Dose (mg) / Concentration (mg/mL)

Volume to infuse (mL) = 375 mg / 2.5 mg/mL

Volume to infuse (mL) = 150 mL (This confirms that the full bag volume delivers the prescribed dose)

Calculate the infusion rate (mL/hour):

Infusion rate (mL/hour) = Total volume to infuse (mL) / Infusion time (hours)

Infusion rate (mL/hour) = 150 mL / 1.5 hours

Infusion rate (mL/hour) = 100 mL/hour

Calculate the drip rate (drops/minute):

Drip rate (drops/minute) = Infusion rate (mL/hour) x Drip chamber calibration (drops/mL)

Drip rate (drops/minute) = 100 mL/hour x 10 drops/mL

Drip rate (drops/minute) = 1000 drops/hour (convert to minutes)

Drip rate (drops/minute) = 1000 drops/hour / 60 minutes/hour

Drip rate (drops/minute) = 16.67 drops/minute (round to nearest whole number as requested)

Therefore, the nurse should regulate the gravity infusion at approximately 17 drops/minute.

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Correct Answer is ["200"]

Explanation

Here's the calculation:

The medication dose (ciprofloxacin 400 mg) needs to be delivered over the entire infusion duration (1 hour).

The total volume of the IV bag containing the medication (200 mL) is the volume that needs to be infused.

Although the ciprofloxacin itself might be concentrated in a smaller volume within the bag,

the entire bag with both the medication and diluent (dextrose 5% in water) needs to be delivered over the 1-hour timeframe.

Therefore, the infusion pump rate should be set to deliver the entire volume of the bag (200 mL) over the 1-hour duration, resulting in a rate of 200 mL/hour.

Correct Answer is ["440"]

Explanation

While the primary infusion rate (dextrose 5% in water) and the total volume of pantoprazole solution are provided, the pantoprazole infusion doesn't directly affect the rate of the primary DSW infusion.

Here's the breakdown:

Primary Infusion:

Dextrose 5% in water (DSW) at 125 mL/hour (given) - This rate remains constant throughout the secondary infusion.

Secondary Infusion:

Pantoprazole 40 mg total dose (given)

Premixed solution volume: 110 mL (given)

Infusion duration: 15 minutes (given) = 0.25 hours (convert minutes to hours)

The nurse programs the secondary infusion pump to deliver the 110 mL pantoprazole solution over 0.25 hours, independent of the primary DSW infusion.

Therefore, the nurse should program the secondary infusion pump to deliver a rate of:

Delivery rate (mL/hour) = Total volume (mL) / Infusion time (hours)

Delivery rate (mL/hour) = 110 mL / 0.25 hours

Delivery rate (mL/hour) = 440 mL/hour (This is the rate for the pantoprazole solution only)

In conclusion:

The primary DSW infusion rate remains at 125 mL/hour.

The secondary pantoprazole infusion rate is 440 mL/hour, but it delivers the total dose (110 mL) over the 15-minute timeframe.

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Naxlex Comprehensive Predictor Exams

A client receives a prescription for IV ciprofloxacin 400 mg every 12 hours, which is to be infused over an hour. The IV bag contains ciprofloxacin 400 mg in dextrose 5% in water (DW) 200 mL. How many mL/hr should the nurse program the infusion pump to deliver? (Enter numerical value only.)

Correct Answer is ["200"]

Explanation

Correct Answer is ["440"]

Explanation

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