The healthcare provider prescribes ganciclovir 375 mg intravenous (IV) every 12 hour to infuse over 90 minutes. The pharmacy delivers ganciclovir 375 mg in a 150 mL IV bag. How many drops/minute should the nurse regulate the gravity infusion using a drip chamber that delivers 10 drops/mL? (Enter numerical value only. If rounding is required, round to the nearest whole number.)
The Correct Answer is ["17"]
Here's how to calculate the drip rate (drops/minute) for the ganciclovir infusion:
1. We know:
Ganciclovir dose: 375 mg (given)
Infusion bag volume: 150 mL (given)
Infusion time: 90 minutes (given) = 1.5 hours (convert minutes to hours)
Drip chamber calibration: 10 drops/mL (given)
2. We need to find:
Drip rate (drops/minute)
3. Steps:
Calculate the concentration of ganciclovir in the bag (assuming all medication is in the bag):
Concentration (mg/mL) = Dose (mg) / Volume (mL)
Concentration (mg/mL) = 375 mg / 150 mL
Concentration (mg/mL) = 2.5 mg/mL
Calculate the total volume to infuse (considering the prescribed dose):
We already know the volume of the bag (150 mL), but this might contain more volume than needed to deliver the prescribed dose.
Calculate the volume to infuse based on the dose and concentration:
Volume to infuse (mL) = Dose (mg) / Concentration (mg/mL)
Volume to infuse (mL) = 375 mg / 2.5 mg/mL
Volume to infuse (mL) = 150 mL (This confirms that the full bag volume delivers the prescribed dose)
Calculate the infusion rate (mL/hour):
Infusion rate (mL/hour) = Total volume to infuse (mL) / Infusion time (hours)
Infusion rate (mL/hour) = 150 mL / 1.5 hours
Infusion rate (mL/hour) = 100 mL/hour
Calculate the drip rate (drops/minute):
Drip rate (drops/minute) = Infusion rate (mL/hour) x Drip chamber calibration (drops/mL)
Drip rate (drops/minute) = 100 mL/hour x 10 drops/mL
Drip rate (drops/minute) = 1000 drops/hour (convert to minutes)
Drip rate (drops/minute) = 1000 drops/hour / 60 minutes/hour
Drip rate (drops/minute) = 16.67 drops/minute (round to nearest whole number as requested)
Therefore, the nurse should regulate the gravity infusion at approximately 17 drops/minute.
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Related Questions
Correct Answer is ["4.8"]
Explanation
The vial is labeled as “100 mg per 4 mL.”
This means that each mL contains 25 mg of the medication (100 mg / 4 mL = 25 mg/mL).
The nurse needs to administer 120 mg of the medication.
To find out how many mL this is, we divide the dose by the concentration:
VolumeinmL = 120mg / 25mg/mL = 4.8mL
If rounding is required to the nearest tenth, the nurse should administer 4.8 mL of the medication.
Correct Answer is ["0.6"]
Explanation
Here's the corrected calculation for the volume to be administered:
Dosage: 60 mg
Concentration: 100 mg/mL
Volume to administer:
Volume (mL) = Dosage (mg) / Concentration (mg/mL)
Volume (mL) = 60 mg / 100 mg/mL
Volume (mL) = 0.6 mL
Therefore, the nurse should administer 0.6 mL of enoxaparin sodium injection.
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