The healthcare provider prescribes ganciclovir 375 mg intravenous (IV) every 12 hour to infuse over 90 minutes. The pharmacy delivers ganciclovir 375 mg in a 150 mL IV bag. How many drops/minute should the nurse regulate the gravity infusion using a drip chamber that delivers 10 drops/mL? (Enter numerical value only. If rounding is required, round to the nearest whole number.)
The Correct Answer is ["17"]
Here's how to calculate the drip rate (drops/minute) for the ganciclovir infusion:
1. We know:
Ganciclovir dose: 375 mg (given)
Infusion bag volume: 150 mL (given)
Infusion time: 90 minutes (given) = 1.5 hours (convert minutes to hours)
Drip chamber calibration: 10 drops/mL (given)
2. We need to find:
Drip rate (drops/minute)
3. Steps:
Calculate the concentration of ganciclovir in the bag (assuming all medication is in the bag):
Concentration (mg/mL) = Dose (mg) / Volume (mL)
Concentration (mg/mL) = 375 mg / 150 mL
Concentration (mg/mL) = 2.5 mg/mL
Calculate the total volume to infuse (considering the prescribed dose):
We already know the volume of the bag (150 mL), but this might contain more volume than needed to deliver the prescribed dose.
Calculate the volume to infuse based on the dose and concentration:
Volume to infuse (mL) = Dose (mg) / Concentration (mg/mL)
Volume to infuse (mL) = 375 mg / 2.5 mg/mL
Volume to infuse (mL) = 150 mL (This confirms that the full bag volume delivers the prescribed dose)
Calculate the infusion rate (mL/hour):
Infusion rate (mL/hour) = Total volume to infuse (mL) / Infusion time (hours)
Infusion rate (mL/hour) = 150 mL / 1.5 hours
Infusion rate (mL/hour) = 100 mL/hour
Calculate the drip rate (drops/minute):
Drip rate (drops/minute) = Infusion rate (mL/hour) x Drip chamber calibration (drops/mL)
Drip rate (drops/minute) = 100 mL/hour x 10 drops/mL
Drip rate (drops/minute) = 1000 drops/hour (convert to minutes)
Drip rate (drops/minute) = 1000 drops/hour / 60 minutes/hour
Drip rate (drops/minute) = 16.67 drops/minute (round to nearest whole number as requested)
Therefore, the nurse should regulate the gravity infusion at approximately 17 drops/minute.
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Related Questions
Correct Answer is ["0.4"]
Explanation
Here's the breakdown of the calculation:
The medication vial is labeled 1,200,000 units/2 mL, which means there are 1,200,000 units of penicillin G per every 2 mL of the medication.
We need to find out how many mL are needed to administer the prescribed dose of 240,000 units.
To do this, we can divide the desired dose (240,000 units) by the concentration of the medication (units per mL).
Calculation:
Dose per mL = 1,200,000 units / 2 mL = 600,000 units/mL
Desired dose / Dose per mL = 240,000 units / 600,000 units/mL = 0.4 mL
Rounding to the nearest tenth, the nurse should administer 0.4 mL of Penicillin G procaine.
Correct Answer is ["45"]
Explanation
The infusion rate is given as 45 mL/hour.
We know that 1 hour is 60 minutes, so we can convert the rate to mL/minute:
RateinmL/minute = RateinmL/hour /divide by 60minutes/hour
= 45mL/hour / 60minutes/hour ≈ 0.75mL/minute
The volume-control administration set with a microdrop chamber delivers 60 microdrops/mL.
Therefore, the rate in microdrops/minute would be:
Rateinmicrodrops/minute = RateinmL/minute×DropspermL = 0.75mL/minute × 60microdrops/mL = 45microdrops/minute
However, the question asks to round the answer to the nearest whole number.
So, the nurse should regulate the infusion to deliver 45 microdrops/minute.
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