The nurse is administering SUBO enoxaparin to a client following knee replacement surgery to prevent a deep vein thrombosis. Which laboratory result requires immediate action by the nurse?

Reference Range:

Hematocrit [42% to 52% (0.42 to 0.52 volume fraction)] Platelets [150,000 to 400,000/mm3 (150 to 400 x 109/L]] Creatinine [0.5 to 1.1 mg/dL (44 to 97 pmol/L)]

Blood Urea Nitrogen (BUN) [10 to 20 mg/dL (3.6 to 7.1 mmol/L)]

A. Gout: Aspirin is not typically used for treating gout. Gout is commonly treated with medications like allopurinol or colchicine, and nonsteroidal anti-inflammatory drugs (NSAIDs) are used selectively.
B. Sepsis: Aspirin is not a primary treatment for sepsis. Sepsis is usually treated with antibiotics, fluid resuscitation, and supportive care.
C. Myocardial infarction: Aspirin is beneficial for preventing further myocardial infarctions (heart attacks) in patients with a history of cardiovascular events or at high risk. It works by inhibiting platelet aggregation, thereby reducing the risk of blood clot formation that can lead to heart attacks.
D. Rheumatoid arthritis: Although aspirin can be used for symptomatic relief in rheumatoid arthritis due to its anti-inflammatory properties, it is not the primary treatment. Other medications, such as disease-modifying antirheumatic drugs (DMARDs) and nonsteroidal anti-inflammatory drugs (NSAIDs), are typically used.

A) Protect the skin from sunlight while taking the drug: Tetracycline is known to increase sensitivity to sunlight, leading to a higher risk of sunburn and skin reactions. Advising clients to protect their skin from sun exposure and to use sunscreen is essential to prevent these adverse effects. This precaution helps mitigate the risk of photosensitivity reactions that are commonly associated with tetracycline use.
B) Take with orange juice to enhance gastrointestinal (GI) absorption: Tetracycline should not be taken with dairy products or antacids, as they can bind with the medication and reduce its absorption. While orange juice can enhance absorption, this is not a standard recommendation for tetracycline. Instead, it is generally advised to take tetracycline with water and avoid substances that could interfere with its absorption.
C) Return to the clinic weekly to obtain serum drug levels: Tetracycline typically does not require regular monitoring of serum drug levels, as it does not have a narrow therapeutic index like some other drugs. Instead, patients are generally advised on how to manage side effects and adherence to the medication regimen, rather than frequent clinic visits for drug level monitoring.
D) Take with milk or antacids to prevent gastrointestinal (GI) irritation: Milk and antacids should be avoided when taking tetracycline because they can bind to the medication and significantly reduce its effectiveness. This instruction could lead to decreased therapeutic efficacy and should be avoided. Tetracycline should be taken on an empty stomach to ensure optimal absorption, avoiding interactions with these substances.