The nurse planning care for a child with nephrotic syndrome knows the classification of medication used to reduce edema in nephrotic syndrome is:
Steroids
Antibiotics
Fungicides
Analgesics
The Correct Answer is A
Choice A reason: Nephrotic syndrome causes massive proteinuria, hypoalbuminemia, and edema due to reduced oncotic pressure. Steroids, like prednisone, reduce glomerular inflammation, decrease protein leakage, and restore oncotic pressure, alleviating edema. By targeting the underlying immune-mediated damage, steroids effectively reduce fluid retention, making them the primary medication class for managing edema in this condition.
Choice B reason: Antibiotics treat bacterial infections, which nephrotic syndrome patients are prone to due to immunoglobulin loss, but they do not address edema. Edema results from hypoalbuminemia, not infection. Antibiotics are used for complications like peritonitis, not for reducing fluid retention, making them ineffective for the primary management of nephrotic syndrome edema.
Choice C reason: Fungicides treat fungal infections, which are rare in nephrotic syndrome unless immunocompromised from prolonged steroid use. Edema in nephrotic syndrome stems from proteinuria and low albumin, not fungal pathology. Fungicides have no role in reducing fluid retention, making them irrelevant for addressing the primary pathophysiological mechanism of edema.
Choice D reason: Analgesics relieve pain, which is not a primary feature of nephrotic syndrome. Edema results from hypoalbuminemia, causing fluid shifts into interstitial spaces. Pain management does not address this mechanism or reduce fluid retention. Steroids target the root cause, making analgesics inappropriate for managing edema in nephrotic syndrome.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: Syrup of ipecac is obsolete for acetaminophen overdose, as it delays definitive treatment like N-acetylcysteine. Acetaminophen causes hepatotoxicity via toxic metabolites, requiring specific antidote administration. Ipecac risks aspiration and is ineffective post-gastric lavage, making it an inappropriate choice for managing this potentially life-threatening overdose.
Choice B reason: Vitamin K treats bleeding from anticoagulant overdose, not acetaminophen toxicity, which causes hepatotoxicity by depleting glutathione, leading to liver damage. Vitamin K does not address acetaminophen’s metabolic effects, making it irrelevant. N-acetylcysteine is needed to restore glutathione and detoxify metabolites, making this choice incorrect.
Choice C reason: N-acetylcysteine is the antidote for acetaminophen overdose, replenishing glutathione to detoxify the toxic metabolite NAPQI, preventing liver damage. Administered post-gastric lavage, it reduces hepatotoxicity risk, especially if given within 8 hours of ingestion, making it the expected treatment to protect the child’s liver function.
Choice D reason: Activated charcoal adsorbs toxins in the gut but is less effective post-gastric lavage, as the stomach is already cleared. Acetaminophen’s rapid absorption requires N-acetylcysteine to prevent hepatotoxicity. Charcoal may be used early but is secondary to the antidote, making it less critical in this scenario.
Correct Answer is D
Explanation
Choice A reason: Long-acting insulins, like glargine, provide basal coverage over 24 hours with no peak. Regular insulin has a shorter duration (6-8 hours) and peak (2-4 hours), making it unsuitable for basal control. Its rapid onset classifies it as short-acting, not long-acting, for managing postprandial glucose spikes in diabetes.
Choice B reason: Rapid-acting insulins, like aspart, have an onset of 10-15 minutes and peak at 1-2 hours. Regular insulin has a slower onset (30-60 minutes) and longer duration (6-8 hours), making it short-acting, not rapid-acting. This distinction is critical for timing insulin administration in diabetes management.
Choice C reason: Intermediate-acting insulins, like NPH, have an onset of 1-2 hours and duration of 12-18 hours. Regular insulin’s shorter duration (6-8 hours) and peak (2-4 hours) classify it as short-acting, used for prandial coverage, not intermediate basal control, making this an incorrect classification.
Choice D reason: Regular insulin is short-acting, with an onset of 30-60 minutes, peak at 2-4 hours, and duration of 6-8 hours. It effectively controls postprandial glucose spikes in diabetes by mimicking physiological insulin release. This classification guides its use in meal-time dosing, making it the correct choice.
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