The practical nurse (PN) is discharging a client who had an anaphylactic reaction following administration of ampicillin. Which instruction is most important for the PN to provide this client?

Tell the client to take medications with food to decrease the possibility of future reactions

Instruct the client to wear a medic alert bracelet so penicillin will not be given again

Tell the client to keep epinephrine on hand for self-administration in case a reaction occurs again

Inform the client that it is essential to take all of the prescribed ampicillin

Answer and Explanation

The Correct Answer is B

Choice A reason: Taking medications with food may reduce gastric irritation but does not prevent anaphylactic reactions to penicillin, which are immune-mediated. This advice is irrelevant for avoiding future allergic responses, as it does not address the systemic hypersensitivity triggered by penicillin exposure.

Choice B reason: A medic alert bracelet is critical for a client with a penicillin anaphylaxis history, as it alerts healthcare providers to avoid penicillin, preventing potentially fatal allergic reactions. Anaphylaxis involves IgE-mediated histamine release, and re-exposure risks rapid, life-threatening symptoms, making this the most important instruction.

Choice C reason: Keeping epinephrine is useful for managing anaphylaxis but is secondary to prevention. A medic alert bracelet proactively avoids penicillin exposure, reducing the need for emergency intervention. Epinephrine treats symptoms but does not address the root cause of re-exposure risk.

Choice D reason: Taking all prescribed ampicillin is dangerous, as the client had an anaphylactic reaction, indicating a severe allergy. Continuing the drug risks recurrent, potentially fatal reactions. This choice is incorrect, as it contradicts the need to avoid the allergen entirely.

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Correct Answer is A

Explanation

Choice A reason: Cephalexin, a cephalosporin, has a 5–10% cross-reactivity risk with penicillin allergies due to similar beta-lactam structures. An anaphylactic history increases the risk of severe reactions. Contacting the provider ensures safety, potentially leading to an alternative antibiotic to prevent life-threatening allergic responses.

Choice B reason: Monitoring for rash or hives is reactive and insufficient for a client with a penicillin anaphylaxis history. Cephalexin’s cross-reactivity risk requires proactive avoidance, not just observation, as anaphylaxis can occur rapidly, making this choice inadequate compared to provider consultation.

Choice C reason: Giving cephalexin with an antihistamine does not prevent anaphylaxis, which can be rapid and severe in penicillin-allergic clients. Antihistamines mitigate mild allergies but are ineffective against severe reactions. This choice is unsafe without confirming the drug’s appropriateness first.

Choice D reason: Administering cephalexin as prescribed ignores the significant risk of cross-reactivity with penicillin, given the client’s anaphylactic history. This could trigger a life-threatening reaction, as cephalosporins share structural similarities with penicillins, making immediate administration without verification dangerous.

A. Withhold the next dose and contact the healthcare provider B. Obtain a cooling blanket from the hospital central supply department C. Take the client to a quiet area and provide reassurance D. Administer a PRN prescription for benzodiazepine and acetaminophen

Correct Answer is A

Explanation

Choice A reason: Restlessness, tachycardia, fever, and hypertension suggest serotonin syndrome, a life-threatening paroxetine side effect due to excessive serotonin. Withholding the dose and contacting the provider prevents further serotonin accumulation, allowing urgent assessment and intervention to stabilize the client’s neurological and cardiovascular status.

Choice B reason: A cooling blanket addresses fever but is not the first action for serotonin syndrome. Withholding paroxetine and consulting the provider are critical to stop the syndrome’s progression, as fever is a symptom, not the cause, making this choice secondary to halting the drug.

Choice C reason: Taking the client to a quiet area may reduce stimulation but does not address serotonin syndrome’s physiological cause. Paroxetine’s serotonin excess drives symptoms, requiring drug cessation and medical intervention, not just reassurance, as this condition can rapidly worsen, making this choice inadequate.

Choice D reason: Administering benzodiazepine and acetaminophen is premature without provider guidance, as serotonin syndrome requires specific treatments, like cyproheptadine. Paroxetine must be stopped first, and the provider consulted to confirm diagnosis and manage symptoms, making this choice unsafe and reactive.

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The practical nurse (PN) is discharging a client who had an anaphylactic reaction following administration of ampicillin. Which instruction is most important for the PN to provide this client?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A client with a history of anaphylactic reaction to penicillin receives a prescription for cephalexin 500 mg by mouth twice daily. Which action should the practical nurse (PN) take?

Correct Answer is A

Explanation

The practical nurse (PN) is caring for a client receiving a prescription for paroxetine who suddenly exhibits restlessness, tachycardia, fever, and elevated blood pressure. Which action should the PN implement first?

Correct Answer is A

Explanation

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