A client receives a new prescription for montelukast. Which information should the nurse include in the client's teaching?

A. Hypertension:

Hypertension (high blood pressure) is not typically associated with piperacillin-tazobactam. While monitoring blood pressure is important during infusions, it is not a reason to stop the infusion on its own.

B. Pupillary constriction:

Pupillary constriction (miosis) is not a common adverse reaction to piperacillin-tazobactam. It is not a primary reason to stop the infusion.

When a client receiving an infusion of piperacillin-tazobactam for a urinary tract infection reports not feeling well, the manifestation that the nurse should identify as a reason to stop the infusion is:

C. Bradycardia.

Explanation: Bradycardia (a slow heart rate) can be an adverse reaction to piperacillin-tazobactam. While it is important to monitor vital signs during the administration of antibiotics, particularly for signs of an allergic reaction or anaphylaxis, bradycardia is a specific manifestation that can be associated with this medication. Stopping the infusion and assessing the client's condition further is appropriate if bradycardia occurs.

D. Scratchy throat:

A scratchy throat could be a sign of an allergic reaction but is not specific to piperacillin-tazobactam. Other signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, would be more concerning. In such cases, the infusion should be stopped and appropriate interventions initiated.

Here are the potential effects of each drug on captopril's blood pressure effects:

Losartan: Decrease - Losartan is an angiotensin receptor blocker (ARB) that can lower blood pressure. When used in combination with captopril (an ACE inhibitor), it may enhance the antihypertensive effects, potentially leading to an additive blood pressure-lowering effect.

Ibuprofen: Increase - Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), can lead to sodium and water retention and potentially raise blood pressure. When combined with captopril, it may diminish captopril's blood pressure-lowering effects.

Amlodipine: No Effect - Amlodipine is a calcium channel blocker used to treat high blood pressure. It has a different mechanism of action than captopril and combining them typically does not interfere significantly with each other's effects.

Sulfa: No Effect - Sulfonamides (sulfa drugs) are antibiotics that generally do not directly impact blood pressure or interact with antihypertensive medications like captopril in terms of blood pressure effects.

Insulin lispro: No Effect - Insulin lispro is used to manage blood glucose levels in diabetes. While uncontrolled blood glucose can indirectly affect blood pressure, insulin lispro itself does not directly interact with captopril's blood pressure effects.

Please note that drug interactions can be complex, and individual responses may vary. It's crucial for the healthcare provider to monitor the patient's blood pressure and adjust medications as needed to achieve optimal control.