The practical nurse (PN) is reinforcing discharge instructions for a client with metastatic cancer who is prescribed morphine for bone pain. Which information from the client indicates to the PN an understanding of the medication?

Choice A reason: Rivaroxaban, a direct oral anticoagulant, inhibits factor Xa, increasing bleeding risk. Bruising on arms and legs may indicate excessive anticoagulation, potentially leading to severe hemorrhage. Immediate reporting is critical to assess bleeding risk, adjust dosing, or initiate interventions to prevent life-threatening complications.

Choice B reason: Genital itching and burning with discharge suggest a possible infection or allergic reaction, not a direct adverse effect of rivaroxaban. These symptoms are unrelated to its anticoagulant mechanism, which primarily affects hemostasis, making this choice incorrect for immediate reporting.

Choice C reason: Diminished taste and smell are not recognized side effects of rivaroxaban. These symptoms may relate to other conditions, like neurological or infectious issues, but do not reflect the drug’s anticoagulant effects. This choice is irrelevant to rivaroxaban’s adverse effect profile.

Choice D reason: Hard, dry stools indicate constipation, a non-urgent side effect not typically associated with rivaroxaban. While gastrointestinal issues may occur, bleeding risks are more critical. This symptom does not warrant immediate reporting compared to bruising, which signals potential hemorrhage.

Choice A reason: Using an Amsler grid monitors macular degeneration, not sildenafil-related visual changes, which include color tinting or blurred vision due to PDE5 inhibition affecting retinal blood flow. This is not a standard monitoring tool for sildenafil side effects, making it inappropriate for this context.

Choice B reason: Instilling eye drops is irrelevant, as sildenafil’s visual changes are systemic, caused by its effect on retinal phosphodiesterase, not a local eye condition treatable with drops. No evidence supports eye drops for this side effect, making this choice incorrect and ineffective.

Choice C reason: Wearing dark glasses may reduce light sensitivity but does not address sildenafil’s visual side effects, like blue-green color distortion, caused by altered retinal signaling. This is a temporary, drug-induced effect, and glasses do not mitigate the underlying issue, making this choice inadequate.

Choice D reason: Reporting visual changes immediately is critical, as sildenafil can cause rare but serious effects like non-arteritic anterior ischemic optic neuropathy, impairing retinal blood flow. Prompt reporting allows the provider to assess severity, adjust dosing, or discontinue the drug to prevent permanent vision loss.