What are the primary proteins responsible for viral entry and fusion in measles infection?
Nucleoprotein (N) and phosphoprotein (P)
Matrix protein (M) and large protein (L)
Fusion protein (F) and hemagglutinin protein (H)
Nucleoprotein (N) and matrix protein (M)
The Correct Answer is C
Choice A rationale:
Nucleoprotein (N) and phosphoprotein (P) are not responsible for viral entry and fusion in measles infection. These proteins are involved in viral replication and assembly, not the initial entry into host cells.
Choice B rationale:
Matrix protein (M) and large protein (L) are not responsible for viral entry and fusion in measles infection. The matrix protein plays a role in the assembly and structure of the virus, while the large protein is involved in viral replication and transcription.
Choice C rationale:
Fusion protein (F) and hemagglutinin protein (H) are the primary proteins responsible for viral entry and fusion in measles infection. The hemagglutinin protein allows the virus to bind to specific receptors on host cells, while the fusion protein facilitates the fusion of the viral envelope with the host cell membrane, allowing the virus to enter the cell.
Choice D rationale:
Nucleoprotein (N) and matrix protein (M) are not directly involved in viral entry and fusion. Nucleoprotein plays a role in protecting the viral RNA, and the matrix protein is involved in viral assembly and budding.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Measles is transmitted through respiratory droplets and person-to-person contact.
Choice A rationale:
Measles is not transmitted through contaminated water sources. It is a highly contagious viral infection that primarily spreads through respiratory droplets when an infected person coughs or sneezes.
Choice B rationale:
Measles is not transmitted through contact with infected animals. It is a human-specific virus and does not infect animals.
Choice C rationale:
This is the correct choice. Measles is primarily transmitted through respiratory droplets when an infected person coughs or sneezes. It can also spread through direct contact with respiratory secretions or airborne particles.
Choice D rationale:
Measles is not transmitted through exposure to contaminated food. The virus is not foodborne, and the main mode of transmission is person-to-person through respiratory droplets.
Correct Answer is D
Explanation
Choice A rationale:
The parent's statement about diarrhea leading to dehydration and electrolyte imbalance is correct. Measles can cause gastrointestinal symptoms, including diarrhea, which can lead to dehydration. Dehydration can occur due to fluid loss from diarrhea, and electrolyte imbalances can result from the loss of essential minerals. This statement reflects accurate understanding by the parent and does not indicate a need for further teaching.
Choice B rationale:
The parent's statement about pneumonia being the most common cause of death from measles in children is accurate. Measles can lead to respiratory complications, and pneumonia is one of the severe complications associated with the disease. The statement demonstrates the parent's awareness of a potential complication and is correct, indicating no need for further teaching.
Choice C rationale:
The parent's statement about encephalitis occurring in children within 1 week of rash onset and having a mortality rate of 10 to 20 percent is correct. Encephalitis is a rare but serious complication of measles that can lead to inflammation of the brain. The timeframe mentioned and the mortality rate are consistent with the known characteristics of measles-related encephalitis. This response shows good knowledge, and there is no need for further teaching.
Choice D rationale:
The parent's statement about SSPE (Subacute Sclerosing Panencephalitis) being a rare but fatal complication of measles that occurs years after infection and can be effectively treated with antiviral medications is incorrect. SSPE is indeed a rare but fatal complication of measles that occurs several years after initial infection. Unfortunately, there is no known cure for SSPE, and antiviral medications have not been proven to be effective in treating the condition. This statement indicates a need for further teaching to correct the misinformation and ensure the parent understands the seriousness of SSPE.
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