What concept is considered when generic drugs are substituted for brand-name drugs?

Half Life.

Critical concentration.

Distribution.

Bioavailability.

Answer and Explanation

The Correct Answer is D

Choice A rationale

The half-life of a drug refers to the time it takes for the plasma concentration of a drug to reduce by half. It is not a primary consideration when substituting generic drugs for brand-name drugs.

Choice B rationale

Critical concentration is the amount of a drug needed to achieve therapeutic effects. While important, it is not the main factor in generic substitution.

Choice C rationale

Distribution describes how a drug is dispersed throughout the body's tissues and fluids. This factor is crucial for drug efficacy but not directly related to substituting generic drugs.

Choice D rationale

Bioavailability is the degree and rate at which an active drug ingredient is absorbed and becomes available at the site of action. Generic drugs must have the same bioavailability as brand-name drugs to ensure they are just as effective.

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Correct Answer is D

Explanation

Choice A rationale

Increased jugular venous pressure is more commonly associated with right-sided heart failure, where blood backs up into the venous system.

Choice B rationale

Liver enlargement is also indicative of right-sided heart failure due to congestion of the liver blood vessels.

Choice C rationale

Increased pulse rate can occur in both left and right-sided heart failure but is not a specific indicator of worsening left-sided failure.

Choice D rationale

Increased crackles in lung fields indicate fluid accumulation in the lungs, a sign of worsening left-sided heart failure. Left-sided heart failure leads to pulmonary congestion due to inadequate pumping of blood from the left ventricle.

A. Treatment of narcotic dependence. B. Treatment of alcohol dependence. C. Reversal of tachycardia. D. Reversal of bronchoconstriction.

Correct Answer is A

Explanation

Choice A rationale

Treatment of narcotic dependence involves using a narcotics antagonist to block the effects of narcotics. This helps prevent relapse in patients recovering from narcotic addiction by decreasing cravings and withdrawal symptoms.

Choice B rationale

Treatment of alcohol dependence does not typically involve narcotics antagonists. Instead, medications like disulfiram or naltrexone are used to manage alcohol dependence.

Choice C rationale

Reversal of tachycardia is not an indication for a narcotics antagonist. Tachycardia is usually managed with medications like beta-blockers or calcium channel blockers.

Choice D rationale

Reversal of bronchoconstriction is not an indicator for narcotics antagonists. Bronchoconstriction is usually treated with bronchodilators such as albuterol or ipratropium.

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What concept is considered when generic drugs are substituted for brand-name drugs?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

What assessment finding would indicate the patient's left-sided heart failure is worsening?

Correct Answer is D

Explanation

Identify one indicator for a narcotics antagonist to be prescribed.

Correct Answer is A

Explanation

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