What concept is considered when generic drugs are substituted for brand-name drugs?
Half Life.
Critical concentration.
Distribution.
Bioavailability.
The Correct Answer is D
Choice A rationale
The half-life of a drug refers to the time it takes for the plasma concentration of a drug to reduce by half. It is not a primary consideration when substituting generic drugs for brand-name drugs.
Choice B rationale
Critical concentration is the amount of a drug needed to achieve therapeutic effects. While important, it is not the main factor in generic substitution.
Choice C rationale
Distribution describes how a drug is dispersed throughout the body's tissues and fluids. This factor is crucial for drug efficacy but not directly related to substituting generic drugs.
Choice D rationale
Bioavailability is the degree and rate at which an active drug ingredient is absorbed and becomes available at the site of action. Generic drugs must have the same bioavailability as brand-name drugs to ensure they are just as effective.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale
True. Xanthine derivatives like theophylline can cause serious adverse effects, including brain damage, when blood levels become too high. It is critical to monitor theophylline levels to prevent toxicity and associated neurological complications.
Choice B rationale
False. If xanthine levels remain within therapeutic ranges, the risk of brain damage is minimized. However, this statement is incorrect as it does not acknowledge the potential severity of the adverse effects linked to elevated theophylline levels.
Correct Answer is D
Explanation
Choice A rationale
Serotonin does not compete with anticholinergic agents at muscarinic acetylcholine receptor sites; anticholinergics target these receptors to inhibit the parasympathetic nervous system.
Choice B rationale
Anticholinergics do not increase norepinephrine at the neuromuscular junction.
Choice C rationale
Nicotinic receptors are primarily affected by different classes of drugs, such as neuromuscular blockers.
Choice D rationale
Anticholinergics inhibit the actions of the parasympathetic nervous system by blocking muscarinic receptors, reducing bodily functions like saliva production, digestion, and urination.
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