The nurse is preparing to administer amoxicillin (Amoxil) to a patient and learns that the patient previously experienced a rash when taking penicillin.
Which action will the nurse take?

Choice A rationale

This choice is incorrect. Cholinergic agonists primarily affect acetylcholine receptors, not GABA receptors. GABA receptors are involved in the inhibitory neurotransmission in the central nervous system and are the target of different drug classes, such as benzodiazepines and barbiturates, which are not related to cholinergic agonists.

Choice B rationale

This choice is incorrect. Cholinergic agonists do not decrease norepinephrine activity. Norepinephrine is a neurotransmitter involved in the sympathetic nervous system response, which is different from the cholinergic system. Drugs that decrease norepinephrine activity would have a different mechanism of action, such as adrenergic antagonists.

Choice C rationale

This choice is incorrect. The primary action of cholinergic agonists is not to increase dopamine activity. Dopamine is another neurotransmitter involved in various brain functions, including reward and motor control. Cholinergic agonists specifically target acetylcholine receptors, enhancing their activity, which is not related to dopamine receptors.

Choice D rationale

This choice is correct. Cholinergic agonists increase the activity of acetylcholine receptor sites throughout the body. These drugs mimic the action of acetylcholine, a neurotransmitter that plays a key role in the parasympathetic nervous system, which regulates functions such as muscle contraction, gland secretion, and heart rate. Enhancing acetylcholine activity helps in conditions like myasthenia gravis and certain types of glaucoma.

Choice A rationale

Sympathetic stimulation typically increases the depth and rate of respirations to enhance oxygen delivery to tissues during stress or physical activity.

Choice B rationale

Sympathetic stimulation does not directly increase lung perfusion. It primarily affects the airways to increase airflow.

Choice C rationale

Sympathetic stimulation increases the respiratory rate by activating the respiratory centers in the brain, preparing the body for increased oxygen demand during stress or physical activity.

Choice D rationale

Sympathetic stimulation does not decrease the respiratory rate. It typically increases both the rate and depth of respirations to meet the body's increased oxygen needs. .