Which of the following is/are FDA-approved indication(s) for albuterol sulfate (inhalation)? Select All That Apply.
Prevention of exercise-induced bronchospasm
Allergic Rhinitis
Relief of bronchospasm
Rhinorrhea associated with the Common Cold
Correct Answer : A,C
A. Prevention of exercise-induced bronchospasm is a labeled indication for albuterol sulfate. It is administered prophylactically to stabilize mast cells and prevent airway constriction. This ensures patent airways during physical exertion in patients with hyperreactive airway disease.
B. Allergic rhinitis involves inflammatory responses in the nasal mucosa rather than the lower respiratory tract. Albuterol is a sympathomimetic bronchodilator and lacks the antihistaminic or anti-inflammatory properties required for this condition. It provides no therapeutic benefit for nasal congestion.
C. Relief of bronchospasm in patients with reversible obstructive airway disease is the primary indication. Albuterol acts as a selective beta-2 adrenergic agonist to increase intracellular cyclic adenosine monophosphate. This results in the relaxation of bronchial smooth muscle and rapid bronchodilation.
D. Rhinorrhea associated with the common cold is caused by viral-induced nasal inflammation and increased glandular secretion. Albuterol does not possess the anticholinergic or vasoconstrictive effects needed to reduce nasal discharge. Its pharmacological activity is limited to the beta receptors of the bronchi.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Fluticasone is the generic name for medications such as Flovent or Flonase, representing a different synthetic glucocorticoid. It possesses a high affinity for the glucocorticoid receptor but is a distinct chemical entity from the active ingredient in Pulmicort.
B. Beclomethasone is the generic name for Qvar, a halogenated corticosteroid used for the maintenance treatment of asthma. While it share a similar therapeutic class with Pulmicort, it is not the correct generic identifier for the brand name provided.
C. Budesonide is the generic name for Pulmicort, an inhaled corticosteroid used for maintenance therapy in asthma. It functions by decreasing the synthesis of inflammatory mediators and reducing airway hyperresponsiveness through glucocorticoid receptor activation. This results in potent anti-inflammatory effects.
D. Budesonide and formoterol fumarate dihydrate is the generic combination found in the brand Symbicort. This product includes both a corticosteroid and a long-acting beta-2 agonist. It is not the generic name for the single-ingredient product known as Pulmicort.
Correct Answer is C
Explanation
A. Focalin is the brand name for dexmethylphenidate, which is the d-threo-enantiomer of methylphenidate. It acts primarily as a dopamine and norepinephrine reuptake inhibitor. It does not contain the sulfate or saccharate salts of the amphetamine molecule found in the question.
B. Vyvanse contains lisdexamfetamine dimesylate, a prodrug converted to dextroamphetamine in the blood. While it provides dextroamphetamine, it is a single-molecule formulation rather than a mixture of salts. It lacks the levoamphetamine component found in the mixed salt combination.
C. Adderall is the proprietary name for a combination of 4 different amphetamine salts. It specifically consists of dextroamphetamine saccharate, dextroamphetamine sulfate, amphetamine aspartate monohydrate, and amphetamine sulfate. This mixture provides a specific ratio of 3 to 1 dextroamphetamine to levoamphetamine.
D. Ritalin is the brand name for methylphenidate hydrochloride, a central nervous system stimulant. Its mechanism involves the inhibition of the dopamine transporter and norepinephrine transporter. It is chemically distinct from the phenethylamine derivatives found in amphetamine and dextroamphetamine salt mixtures.
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