When researching information about a drug, the nurse finds that the drug tightly binds to protein. The nurse would interpret this to mean that the drug will:

be released fairly quickly.

have a long duration of action.

be excreted quickly.

lead to toxicity when given.

Answer and Explanation

The Correct Answer is B

A. A drug that binds tightly to protein is typically released slowly, not quickly, as it remains bound in circulation.

B. Tight binding to proteins usually results in a prolonged duration of action since the drug is released gradually into the bloodstream, leading to sustained therapeutic effects.

C. Drugs that bind tightly to protein are generally not excreted quickly; they remain in circulation longer due to the binding.

D. While toxicity can occur with any drug, tight protein binding does not inherently lead to toxicity; it primarily affects the pharmacokinetics of the drug.

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Free Nursing Study Resources

Correct Answer is A

Explanation

A. Atropine is an anticholinergic medication that increases heart rate by blocking vagal effects on the heart, making it the first-line treatment for symptomatic bradycardia.

B. Cholestyramine is a bile acid sequestrant used to lower cholesterol levels and does not have any effects on heart rate.

C. Inamrinone is a phosphodiesterase inhibitor used in heart failure for inotropic support but is not specifically indicated for bradycardia management.

D. Milrinone is also a phosphodiesterase inhibitor used for heart failure but does not address bradycardia directly.

A. They are under a scheduled drug classification. B. They are ineffective in treating depression or anxiety disorders. C. They can cause gastrointestinal (GI) bleeding and esophageal varices. D. They may cause dangerous interactions with some foods and drugs.

Correct Answer is D

Explanation

A. While MAOIs may have some regulatory considerations, they are not classified under a scheduled drug classification like controlled substances.

B. MAOIs are effective in treating depression and anxiety disorders, which is not the reason for their limited use.

C. Although MAOIs can have some side effects, they are more notably associated with dietary and drug interactions rather than causing GI bleeding or esophageal varices.

D. MAOIs can cause dangerous interactions with foods that contain tyramine (like aged cheeses and fermented products) and certain medications, leading to hypertensive crises, making their use cautious and limiting in clinical practice.

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When researching information about a drug, the nurse finds that the drug tightly binds to protein. The nurse would interpret this to mean that the drug will:

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

When caring for a patient who has been admitted for his heart failure, the nurse observes that the patient is experiencing bradycardia. Which drug should be administered to patients who develop bradycardia?

Correct Answer is A

Explanation

What is the major reason that monoamine oxidase inhibitors (MAOIs) are rarely used in clinical practice today?

Correct Answer is D

Explanation

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