When researching information about a drug, the nurse finds that the drug tightly binds to protein. The nurse would interpret this to mean that the drug will:

be released fairly quickly.

have a long duration of action.

be excreted quickly.

lead to toxicity when given.

Answer and Explanation

The Correct Answer is B

A. A drug that binds tightly to protein is typically released slowly, not quickly, as it remains bound in circulation.

B. Tight binding to proteins usually results in a prolonged duration of action since the drug is released gradually into the bloodstream, leading to sustained therapeutic effects.

C. Drugs that bind tightly to protein are generally not excreted quickly; they remain in circulation longer due to the binding.

D. While toxicity can occur with any drug, tight protein binding does not inherently lead to toxicity; it primarily affects the pharmacokinetics of the drug.

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Free Nursing Study Resources

Correct Answer is A

Explanation

A. "There can be an unsafe reaction between your antidepressant and St. John's wort, which is why taking them both is discouraged." is correct; St. John's wort can reduce the effectiveness of SSRIs and may increase the risk of serotonin syndrome, making it vital for the nurse to address this safety concern.

B. "Herbal remedies often contain unknown doses of the desired ingredient, which can be dangerous." is a valid point, but it does not specifically address the interaction with the client’s current medication.

C. "It's very important that you not take the St. John's wort at the same time of day as your antidepressant." is misleading; the concern is not just about timing but about taking both together at all.

D. "It's very important that you comply with your prescribed treatment." while true, this response does not directly address the specific risks associated with combining St. John's wort and citalopram.

A. nitroglycerin pm for angina B. furosemide 10 mg by mouth daily C. verapamil 80 mg by mouth three times a day D. acetaminophen 650 mg by mouth prn arthritic pain

Correct Answer is A

Explanation

A. Nitroglycerin is contraindicated with erectile dysfunction medications such as sildenafil (Viagra) because both can cause significant drops in blood pressure when used together, potentially leading to severe cardiovascular complications.

B. Furosemide is a diuretic and does not have a direct contraindication with erectile dysfunction medications, although it may contribute to electrolyte imbalances.

C. Verapamil is a calcium channel blocker that does not directly contraindicate the use of erectile dysfunction medications but should be monitored for potential interactions affecting heart rate and blood pressure.

D. Acetaminophen is a pain reliever and does not pose a contraindication for erectile dysfunction medications.

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When researching information about a drug, the nurse finds that the drug tightly binds to protein. The nurse would interpret this to mean that the drug will:

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Correct Answer is A

Explanation

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Correct Answer is A

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