When researching information about a drug, the nurse finds that the drug tightly binds to protein. The nurse would interpret this to mean that the drug will:

be released fairly quickly.

have a long duration of action.

be excreted quickly.

lead to toxicity when given.

Answer and Explanation

The Correct Answer is B

A. A drug that binds tightly to protein is typically released slowly, not quickly, as it remains bound in circulation.

B. Tight binding to proteins usually results in a prolonged duration of action since the drug is released gradually into the bloodstream, leading to sustained therapeutic effects.

C. Drugs that bind tightly to protein are generally not excreted quickly; they remain in circulation longer due to the binding.

D. While toxicity can occur with any drug, tight protein binding does not inherently lead to toxicity; it primarily affects the pharmacokinetics of the drug.

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Correct Answer is A

Explanation

A. Blood pressure is correct because both nitroglycerin and diltiazem can cause vasodilation, leading to hypotension; thus, monitoring blood pressure is crucial for patient safety.

B. Level of consciousness is incorrect; while important, it is not the primary concern in this context.

C. Daily weights are incorrect; they are more relevant for assessing fluid status over time, not immediate drug effects.

D. Respiratory status is incorrect; while monitoring is important, blood pressure takes precedence due to the risk of hypotension associated with these medications.

A. "Metformin stimulates the pancreas to produce more insulin." B. "Metformin increases the absorption of glucose in the intestines." C. "Metformin decreases glucose production in the liver and improves insulin sensitivity." D. "Metformin decreases the breakdown of fat in the body."

Correct Answer is C

Explanation

A. Metformin does not stimulate the pancreas to produce more insulin; that action is characteristic of sulfonylureas.

B. Metformin does not increase the absorption of glucose in the intestines; rather, it works by reducing the amount of glucose released into the bloodstream.

C. Metformin primarily decreases glucose production in the liver and improves insulin sensitivity in peripheral tissues, which helps lower blood sugar levels. This makes it effective for managing type 2 diabetes.

D. While metformin can have effects on fat metabolism, its primary action is not to decrease fat breakdown but to manage blood glucose levels.

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When researching information about a drug, the nurse finds that the drug tightly binds to protein. The nurse would interpret this to mean that the drug will:

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A client with a long-standing diagnosis of angina has been prescribed nitroglycerin and diltiazem. In addition to monitoring the client's heart rate, the nurse should prioritize what assessment?

Correct Answer is A

Explanation

A patient asks how metformin works to control blood sugar. What is the nurse's best response?

Correct Answer is C

Explanation

A client has been prescribed a tricyclic antidepressant and the nurse recognizes the client's associated risk for anticholinergic effects. What should the nurse teach the client about preventing and managing these adverse effects? (Select all that apply.)

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