Which adverse effect unique to vancomycin is caused by histamine release?
Discoloration of body fluids
Ototoxicity
Red-man syndrome
Nephrotoxicity
The Correct Answer is C
A. Discoloration of body fluids:
Vancomycin can cause discoloration of body fluids, particularly urine, resulting in a brownish discoloration. However, this is not caused by histamine release.
B. Ototoxicity:
Ototoxicity refers to damage to the inner ear structures leading to hearing loss or balance problems. While vancomycin can cause ototoxicity, it is not specifically associated with histamine release.
C. Red-man syndrome
Red-man syndrome, also known as red-neck syndrome or red-person syndrome, is a hypersensitivity reaction characterized by flushing of the skin, particularly the upper body and face, resembling a "red man." This reaction is typically associated with the rapid infusion of vancomycin and is caused by the release of histamine from mast cells and basophils. It is not an allergic reaction but rather a non-immunologic response to vancomycin.
D. Nephrotoxicity:
Nephrotoxicity refers to kidney damage caused by certain medications or toxins. While vancomycin can cause nephrotoxicity, it is not specifically associated with histamine release.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Ginger root:
Ginger root is well-known for its anti-nausea and anti-inflammatory properties. It has been used for centuries to alleviate motion sickness, nausea, and vomiting. Ginger works by helping to calm the stomach and alleviate gastrointestinal discomfort. Therefore, ginger root is a suitable herbal supplement for controlling nausea associated with motion sickness.
B. Garlic:
Garlic is not typically used for controlling nausea. While garlic has various health benefits, including cardiovascular and immune support, it is not known for its anti-nausea properties.
C. Kava:
Kava is an herbal supplement used for its anxiolytic and sedative effects. It is not commonly used for controlling nausea and may not be effective for alleviating symptoms of motion sickness.
D. Valerian:
Valerian is an herb primarily used for its sedative and anxiolytic properties. It is not commonly used for controlling nausea and would not be an appropriate choice for alleviating symptoms of motion sickness.
Correct Answer is B
Explanation
A. Changes in mental status:
Changes in mental status are not typically associated with ototoxicity caused by gentamicin. Mental status changes may indicate other systemic effects or adverse reactions, but they are not specific to ototoxicity.
B. Complaints that he is unable to hear the television:
This complaint is highly indicative of ototoxicity. Hearing loss, particularly high-frequency hearing loss, is a common symptom of ototoxicity caused by drugs like gentamicin. Difficulty hearing sounds such as the television, especially at typical volume levels, suggests a potential problem with hearing function.
C. An increase in the BUN and creatinine:
An increase in blood urea nitrogen (BUN) and creatinine levels may indicate kidney damage, which can occur as a result of nephrotoxicity associated with gentamicin use. While nephrotoxicity is a known adverse effect of gentamicin, it is not specific to ototoxicity.
D. Tingling of the extremities:
Tingling of the extremities is not typically associated with ototoxicity caused by gentamicin. This symptom may suggest other neurological or systemic effects but is not specific to ototoxicity.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today