Which class of antibiotic is associated with cartilage toxicity and rupture of the Achilles tendon?
Penicillins
Fluoroquinolones
Aminoglycosides
Sulfonamides
The Correct Answer is B
A. Penicillins:
Penicillins are a class of antibiotics commonly used to treat various bacterial infections. While they are generally well-tolerated and have a low incidence of adverse effects, they are not typically associated with cartilage toxicity or tendon rupture, including the Achilles tendon.
B. Fluoroquinolones:
Fluoroquinolones are broad-spectrum antibiotics known for their effectiveness against a wide range of bacteria. However, they are associated with several significant adverse effects, including cartilage toxicity and tendon rupture. These adverse effects, particularly tendon rupture, are most commonly observed in weight-bearing tendons such as the Achilles tendon. Fluoroquinolones should be used cautiously, especially in populations at higher risk for tendon injuries.
C. Aminoglycosides:
Aminoglycosides are another class of antibiotics used to treat severe bacterial infections. While they have their own set of potential adverse effects, such as nephrotoxicity and ototoxicity, they are not associated with cartilage toxicity or tendon rupture.
D. Sulfonamides:
Sulfonamides are antibiotics that inhibit bacterial growth by interfering with the synthesis of folate. While they can cause various adverse effects, including skin reactions and hematologic abnormalities, they are not associated with cartilage toxicity or tendon rupture.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Take small amounts of food:
This advice suggests eating small, frequent meals when experiencing diarrhea. It aims to reduce the workload on the digestive system and may help alleviate symptoms such as nausea and discomfort. However, while eating small amounts of food can be beneficial, increasing fluid intake is the priority to prevent dehydration associated with diarrhea.
B. Consume large quantities of milk and smoked meat:
Consuming large quantities of milk and smoked meat is not recommended when experiencing diarrhea. Dairy products, including milk, can worsen diarrhea in some individuals, especially those who are lactose intolerant. Similarly, smoked meat may be high in fat and difficult to digest, potentially aggravating gastrointestinal symptoms. Therefore, this advice is not appropriate for managing diarrhea.
C. Increase fluid intake:
Increasing fluid intake is essential when experiencing diarrhea to prevent dehydration. Diarrhea leads to the loss of fluids and electrolytes from the body, which can quickly lead to dehydration if not replenished. Encouraging the patient to drink water, clear broths, oral rehydration solutions, and other electrolyte-rich fluids helps replace lost fluids and maintain hydration levels, making this the correct choice.
D. Take a mild medication to treat the diarrhea along with the ciprofloxacin:
While it may be tempting to take a medication to alleviate diarrhea symptoms, it's crucial to consult a healthcare provider before taking any additional medications, especially when already taking antibiotics like ciprofloxacin. Some anti-diarrheal medications can interfere with the effectiveness of antibiotics or worsen gastrointestinal symptoms. Therefore, it's important to seek medical advice before taking any additional medications.
Correct Answer is D
Explanation
A. Antibiotic dosages below the minimum concentration are prescribed:
This statement is incorrect. When treating MRSA infections, it's essential to prescribe antibiotic dosages that achieve adequate concentrations to effectively combat the resistant bacteria. Suboptimal dosages or inadequate duration of treatment can contribute to treatment failure and the development of antibiotic resistance. Therefore, the nurse should emphasize the importance of prescribing appropriate dosages of antibiotics for MRSA infections.
B. Broad-spectrum antibiotics are used whenever possible:
This statement is not accurate. While broad-spectrum antibiotics may be effective against a wide range of bacteria, they are not always the preferred choice for treating MRSA infections. MRSA is resistant to many antibiotics, including those commonly used as broad-spectrum agents. Therefore, the treatment of MRSA typically involves antibiotics that are specifically effective against this resistant strain, such as vancomycin, daptomycin, linezolid, or other agents based on susceptibility testing. Therefore, the nurse should educate the client that specific antibiotics effective against MRSA are used, rather than relying solely on broad-spectrum antibiotics.
C. Antibiotics are prescribed only when a viral infection is present:
This statement is incorrect. Antibiotics are not effective against viral infections, including those caused by viruses such as influenza or the common cold. MRSA is a bacterial infection, and antibiotics are indicated for its treatment. However, it's essential to use antibiotics judiciously and only when necessary to avoid contributing to antibiotic resistance. The nurse should educate the client that antibiotics are prescribed for bacterial infections like MRSA, but they are not appropriate for viral infections.
D. Infections become resistant to high doses of antibiotics:
This statement is accurate. Overuse or inappropriate use of antibiotics, including high doses, can contribute to the development of antibiotic resistance. Bacteria like MRSA can acquire resistance mechanisms that render antibiotics ineffective, even at high doses. Therefore, it's crucial to use antibiotics judiciously, following appropriate dosing guidelines and duration of treatment, to minimize the risk of antibiotic resistance. The nurse should include this information in the teaching to emphasize the importance of responsible antibiotic use in the management of MRSA infections.
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