Which class of antibiotic is associated with cartilage toxicity and rupture of the Achilles tendon?
Penicillins
Fluoroquinolones
Aminoglycosides
Sulfonamides
The Correct Answer is B
A. Penicillins:
Penicillins are a class of antibiotics commonly used to treat various bacterial infections. While they are generally well-tolerated and have a low incidence of adverse effects, they are not typically associated with cartilage toxicity or tendon rupture, including the Achilles tendon.
B. Fluoroquinolones:
Fluoroquinolones are broad-spectrum antibiotics known for their effectiveness against a wide range of bacteria. However, they are associated with several significant adverse effects, including cartilage toxicity and tendon rupture. These adverse effects, particularly tendon rupture, are most commonly observed in weight-bearing tendons such as the Achilles tendon. Fluoroquinolones should be used cautiously, especially in populations at higher risk for tendon injuries.
C. Aminoglycosides:
Aminoglycosides are another class of antibiotics used to treat severe bacterial infections. While they have their own set of potential adverse effects, such as nephrotoxicity and ototoxicity, they are not associated with cartilage toxicity or tendon rupture.
D. Sulfonamides:
Sulfonamides are antibiotics that inhibit bacterial growth by interfering with the synthesis of folate. While they can cause various adverse effects, including skin reactions and hematologic abnormalities, they are not associated with cartilage toxicity or tendon rupture.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A.Green leafy vegetables:
There is no specific recommendation to avoid green leafy vegetables while taking tetracycline. However, it’s generally advisable to take tetracycline on an empty stomach, as certain foods and supplements containing calcium, magnesium, aluminum, iron, or zinc can interfere with the absorption of tetracycline if consumed concurrently. Green leafy vegetables are not typically high in these minerals, so there is no need to avoid them specifically.
B. Sunlight:
Tetracycline antibiotics, including Sumycin, can increase the skin’s sensitivity to sunlight and UV radiation, leading to an increased risk of sunburn and photosensitivity reactions. Therefore, clients taking tetracycline should be advised to minimize sun exposure, wear protective clothing, and use sunscreen with a high sun protection factor (SPF) to reduce the risk of sunburn and skin damage.
C. Exercise:
There is no specific contraindication to exercise while taking tetracycline. In fact, regular exercise can promote overall health and well-being. However, it’s essential for clients to listen to their bodies and avoid strenuous exercise if they experience any adverse effects or symptoms while taking tetracycline or any other medication.
D. Foods high in tyramine:
Tetracycline antibiotics do not interact with tyramine-containing foods in the same way as certain other classes of antibiotics, such as monoamine oxidase inhibitors (MAOIs). Therefore, there is no specific need to avoid foods high in tyramine while taking tetracycline, as tyramine-related interactions are not typically associated with tetracycline use.
Correct Answer is B
Explanation
A. 36 months:
This duration is longer than typical treatment courses for TB. While treatment for drug-resistant TB may require an extended duration, standard treatment for drug-sensitive TB typically lasts for a shorter period.
B. 6-12 months:
This duration is within the typical range for the treatment of drug-sensitive TB. Standard treatment regimens for drug-sensitive TB usually involve a combination of multiple antibiotics taken for 6 to 9 months, sometimes extending up to 12 months depending on factors such as the severity of the disease and the patient's response to treatment.
C. 2-4 weeks:
This duration is too short for the treatment of TB. TB treatment requires a prolonged course of antibiotics to ensure the complete eradication of the bacteria and to prevent the development of drug resistance.
D. 7-10 days:
This duration is too short for the treatment of TB. TB treatment typically lasts for several months rather than days, as it involves a combination of antibiotics taken for an extended period to effectively treat the infection.
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