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Which combinations of drugs have been found to be effective in managing the pain associated with musculoskeletal and soft tissue inflammation?

A.

Opioid agonists and opioid antagonists

B.

Adjuvants and partial agonists

C.

Nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids

D.

NSAIDs and antidepressants

Answer and Explanation

The Correct Answer is C

A. Opioid agonists and opioid antagonists are incorrect because opioid antagonists (e.g., naloxone) reverse opioid effects rather than enhance pain relief.  
B. Adjuvants and partial agonists are incorrect because while adjuvants can be helpful, partial agonists may not provide adequate pain relief for severe musculoskeletal pain.  
C. NSAIDs and opioids are correct as NSAIDs reduce inflammation and opioids provide stronger analgesia when needed for severe pain.  
D. NSAIDs and antidepressants are incorrect because while some antidepressants help with chronic neuropathic pain, they are not the primary treatment for musculoskeletal and soft tissue inflammation.


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Related Questions

Correct Answer is C

Explanation

A. Chlordiazepoxide is a benzodiazepine used for alcohol withdrawal, but folic acid is not commonly used for managing withdrawal symptoms.
B. Promethazine is an antiemetic, and thiamine is given to prevent Wernicke's encephalopathy, but they are not primarily used to manage withdrawal symptoms.
C. Chlordiazepoxide and lorazepam are both benzodiazepines that are commonly used to manage alcohol withdrawal symptoms by calming the nervous system and preventing seizures or delirium tremens.
D. Lorazepam is appropriate, but promethazine is not typically used to treat alcohol withdrawal symptoms.

Correct Answer is B

Explanation

A. Protein may be restricted in cases of liver failure to prevent ammonia buildup, but calcium isn't typically restricted in liver failure.
B. In acute liver failure and encephalopathy, protein may be restricted to minimize ammonia production, and sodium may be restricted to manage fluid retention and prevent further complications.
C. Fat and magnesium are not typically restricted in this condition.
D. Carbohydrate and potassium are not primary dietary restrictions for acute liver failure.

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